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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Specific investigations: other studies

Currently viewing:

Administrative data

Endpoint:
specific investigations: other studies
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable well-documented publication, which meets basic scientific principles

Data source

Reference
Reference Type:
publication
Title:
Studies of the reactivity of morpholine, 2-mercaptobenzothiazole and 2 of their derivates with amino acids
Author:
Wang, X.; et al.
Year:
1988
Bibliographic source:
Contact Dermatitis 19, 16-21

Materials and methods

Principles of method if other than guideline:
in vitro assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzothiazole-2-thiol
EC Number:
205-736-8
EC Name:
Benzothiazole-2-thiol
Cas Number:
149-30-4
Molecular formula:
C7H5NS2
IUPAC Name:
1,3-benzothiazole-2-thiol
Details on test material:
MBT

Results and discussion

Details on results:
compounds with Cys/MBT, Lys/MBT were detected

Any other information on results incl. tables

The -SH group of MBT may react either via oxidation and/or thioester formation with the carboxylate group of amino acids.

Applicant's summary and conclusion