Registration Dossier
Registration Dossier
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EC number: 220-292-5 | CAS number: 2705-87-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is found to be readily biodegradable and the applied test concentrations are in the range of concentrations that can be expected in the influent of a sewage treatment plant
Reference
Description of key information
The substance was not inhibiting the microbial activity at concentrations that can be expected in the influent of a sewage treatment plant.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 2 mg/L
Additional information
The substance allyl cyclohexylpropionate was not inhibiting to micro-organisms in the study on ready biodegradability at a test concentration of 2 mg/L. This finding is supported by a study on microbial inhibition using Staphylococcus aureus Escherichia coli and other bacterial strains (Morris et al. 1979) and finding no effects at test concentrations of 2 mg/plate applied as 10% (w/v) solutions of the test substance in 95% (v/v) ethanol. In the absence of a test on microbial toxicity, the result of the study on ready biodegradability can be used to derive a NOEC for toxicity to micro-organisms in accordance with ECHA guidance R.7b. The highest test concentration of 2 mg/L applied in the valid study on ready biodegradability was used as the NOEC in the hazard assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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