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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
not applicable
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The reliability rating was 2 because the data are calculated
Qualifier:
according to guideline
Guideline:
other: Computer Model
Principles of method if other than guideline:
Formerly called BCFWIN™, this program estimates fish bioconcentration factor and its logarithm using two different methods. The first is the traditional regression based on log KOW plus any applicable correction factors, and is analogous to the WSKOWWIN™ method. The second is the Arnot-Gobas method, which calculates BCF from mechanistic first principles. BCFBAF also incorporates prediction of apparent metabolism half-life in fish, and estimates BCF and BAF for three trophic levels.
GLP compliance:
no
Radiolabelling:
no
Type:
BCF
Value:
0.895
Basis:
other: Calculated
Time of plateau:
0 d
Calculation basis:
other: EPiSuite 4.0 BCFBAF v3.00
Remarks on result:
other: BCF (Arnot-Gobas method)
Remarks:
Conc.in environment / dose:NA
Type:
BAF
Value:
2.236
Basis:
other: Calculated
Time of plateau:
0 d
Calculation basis:
other: EPI Suite 4.0 BCFBAF v 3.0
Remarks on result:
other: BAF (Arnot-Gobas method)
Remarks:
Conc.in environment / dose:NA

Time of plateau was not applicable to calculated BCF or BAF values. Value of 0 day was entered so as to fill in field since there was no choice to enter none or not applicable.

Validity criteria fulfilled:
yes
Conclusions:
The test substance has a low potential to bioconcentrate, based on the estimated BCF value of 0.8953 and BAF value of 2.236 from EPI Suite v4.0. This indicates that the substance is not likely to be bioaccumulative.
Executive summary:

The test substance has a low potential to bioconcentrate, based on the estimated BCF value of 0.8953 and BAF value of 2.236. In addition, the substance has a calculated Log Kow of 13.3.  As pointed out in the REACH guidance document, Chapter R11.1.3.2 (bioaccumulation assessment, pg 28), “the aquatic BCF of a substance is probably lower than 2000 L/kg if the calculated Log Kow is higher than 10” (ECHA 2008).  Collectively, these calculations support the conclusion that test substance is not expected to be bioaccumulative.

Description of key information

The test substance has a low potential to bioconcentrate, based on the estimated BCF value of 0.8953 and BAF value of 2.236 from EPI Suite v4.0. This indicates that the substance is not likely to be bioaccumulative.


In addition, the substance has a calculated Log Kow of 13.3.  As pointed out in the REACH guidance document, Chapter R11.1.3.2 (bioaccumulation assessment, pg 28), “the aquatic BCF of a substance is probably lower than 2000 L/kg if the calculated Log Kow is higher than 10” (ECHA 2008).  Collectively, these calculations support the conclusion that test substance is not expected to be bioaccumulative.

Key value for chemical safety assessment

BCF (aquatic species):
0.895 dimensionless

Additional information