Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable publication which meets basic scientific principles

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Evaluation of the genotoxic potential of some microbial volatile organic compounds (MVOC) with the comet assay, the micronucleus assay and the HPRT gene mutation assay
Author:
Kreja L and Seidel HJ
Year:
2002
Bibliographic source:
Mutation Research, 513(1-2), 143-150
Reference Type:
secondary source
Title:
No information
Author:
RIFM
Year:
2002
Bibliographic source:
RIFM database

Materials and methods

Type of study / information:
Cytotoxicity
Test guideline
Qualifier:
no guideline available
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methylbutan-1-ol
EC Number:
205-289-9
EC Name:
2-methylbutan-1-ol
Cas Number:
137-32-6
Molecular formula:
C5H12O
IUPAC Name:
2-methylbutan-1-ol
Details on test material:
- Name of test material (as cited in study report): 2-Methyl-1-butanol

Results and discussion

Any other information on results incl. tables

2 -Methyl-1 -butanol: IC50 = 31 mM

MMS: IC50 = 0.2 mM

Applicant's summary and conclusion