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Diss Factsheets
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EC number: 203-650-5 | CAS number: 109-13-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Under the experimental conditions, the 48-hour EL50 of the test substance (75 % t-butylperoxyisobutyrateinisododecane) in a static test system is 231 mg/L expressed as initial loading rate, corresponding to 72.5 mg/L expressed as actual concentration (calculated from geometric means of measured concentrations in the saturated solutions obtained from the loading rates tested), for Daphnia magna.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 72.5 mg/L
Additional information
The acute toxicity of the test substance (75 % t-butyl peroxy isobutyrate in isododecane) was evaluated in the Cladoceran, Daphnia magna STRAUS using a 48-hour static test according to OECD guideline No. 202 and EU method C.2. As the test item is a mixture of poorly soluble components, the water-accomodated fraction (WAF) procedure was applied to prepare the test solutions. A preliminary test which included a limit test and a range-finding test preceded the definitive test. Five loading rates of the test substance were used together with a control at: 0, 50, 100, 200, 400 and 800 mg/L. Twenty daphnids (in four replicates of five) were exposed to each loading rate for 48 hours and immobilization was recorded at 0, 24 and 48 hours.
Initial concentrations of the test item measured in the definitive test solutions were within ± 20% of the corresponding nominal values. The test item was not stable under our experimental conditions since its concentration fell below 80% of the initial value in all solutions during the test (measured concentrations ranged from 4% to 31% of the nominal values after 48 hours). All toxicity results could be based on initial loading rates and also on geometric means of measured concentrations (calculated from the test substance measurements) in test solutions during the corresponding exposure period, i.e. 24 or 48 hours.
Under our experimental conditions, the 48-hour EL50 of the test substance in a static test system is 231 mg/L expressed as initial loading rate, corresponding to (EC50) 72.5 mg/L expressed as actual concentration (calculated from geometric means of measured concentrations in the saturated solutions obtained from the loading rates tested), for Daphnia magna.
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