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EC number: 610-122-1 | CAS number: 433733-94-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26.5.2009 - 28.5.2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- Samples for possible analysis were taken from all test concentrations and the control.
Frequency at t=0 h and t=48 h
Volume 1.5 ml from the approximate centre of the test vessels - Vehicle:
- yes
- Remarks:
- Adjusted ISO medium
- Details on test solutions:
- Preparation of test solutions started with the highest test concentration of 100 mg/L. No special treatment other than careful shaking 5 min of ultrasonic treatment were applied to completely dissolve the test substance in the test medium. The lower test concentrations were prepared by subsequent dilutions in test medium. The final test solutions were all clear and colourless.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia magna (Crustacea, Cladocera) (Straus,1820), at least third generation, obtained by acyclical parthenogenesis under specified breeding conditions.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Test temperature:
- 19.2 - 20.2°C
- pH:
- 7.8 - 8.0
- Dissolved oxygen:
- 9.0 - 9.2mg/l
- Nominal and measured concentrations:
- Nominal test concentrations: 0.1, 1, 10, 100 mg/L
Recovery rate: 97-101% - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate K2Cr2O7
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Key result
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Key result
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Results with reference substance (positive control):
- The actual responses in this reference test with K2Cr20 7 were just outside the ranges of the
expected responses. The sensitivity of this batch of Daphnia magna was slightly higher when
compared with the historical data collected at NOTOX. However, the 48h-EC50 was at the lower
limit (0.3 mg/I) as stated in the ISO 6341 and thus acceptable.
The 24h-EC50 was 0.47 mg/I with a 95% confidence interval between 0.44 and 0.53 mg/I.
The 48h-EC50 was 0.28 mg/I with a 95% confidence interval between 0.25 and 0.31 mg/I. - Validity criteria fulfilled:
- yes
- Conclusions:
- Under the conditions of the present study the test substance did not induce acute immobilisation of Daphnia magna at 100 mg/l after 48 hours of exposure (NOEC). The 48h-EC50 exceeded 100 mg/l based on analytically confirmed nominal concentrations.
According to the classification criteria described in REGULATION (EC) No 1272/2008 (CLP) the product has not to be classified.
Reference
Under the conditions of the present study the test substance did not induce acute immobilisation of Daphnia magna at 100 mg/l after 48 hours of exposure (NOEC). The 48h-EC50 exceeded 100 mg/l based on analytically confirmed nominal concentrations.
Description of key information
Under the conditions of the present study the test substance did not induce acute immobilisation of Daphnia magna at 100 mg/l after 48 hours of exposure (NOEC). The 48h-EC50 exceeded 100 mg/l based on analytically confirmed nominal concentrations.
According to the classification criteria described in REGULATION (EC) No 1272/2008 (CLP) the product has not to be classified.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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