Registration Dossier
Registration Dossier
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EC number: 206-839-0 | CAS number: 381-73-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Acute inhalation toxicity study of Fluoroacetamide in rats
- Author:
- Singh M,Pant,S.C,,Sugendran ,K,Kumar
- Year:
- 2 000
- Bibliographic source:
- Biomedical and Enviormental Sciences,vol 13,issue 2, p-90-96
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- The data is taken from Biomedical & Enviormental Sciences.
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- 2-fluoroacetamide
- EC Number:
- 211-363-1
- EC Name:
- 2-fluoroacetamide
- Cas Number:
- 640-19-7
- IUPAC Name:
- 2-fluoroacetamide
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: aerosol
- Type of inhalation exposure:
- whole body
- Duration of exposure:
- 4 h
- No. of animals per sex per dose:
- 5
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- 137 mg/m³ air
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The lethal concentration LC50 value of Fluoroacetamide in Rats (male/female) was found to be 137 mg/m³ air
- Executive summary:
The lethal concentration (LC50) value of Fluoroacetamide in Rats (male/female) was found to be 137 mg/m³ air, this observed value indicates that the substance is not toxic to inhalation category.
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