Registration Dossier
Registration Dossier
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EC number: 700-483-4 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
- EC50 (96h) > 10 mg/L for freshwater algae [guideline equivalent or similar to EPA OPP 72-2 (Aquatic Invertebrate Acute Toxicity Test)]
- EC50 (96h) > 11.48 mg/L for marine water algae [test followed internal procedures of the laboratory (Static acute Mysid shrimps toxicity test, June 1982)]
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 10 mg/L
- EC10 or NOEC for marine water algae:
- 11.48 mg/L
Additional information
Since RAV 7NG contains as main ingredient 'diallyl 2,2'oxydiethyl dicarbonate', the experimental data from this substance were used in a read-across approach.
Justification for read-across from supporting substance RAV 7AT (diallyl 2,2'-oxydiethyl dicarbonate; CAS 142-22-3; EC 205-528-7): about 70 % of RAV 7NG (EC 700-483-4) consists of components that can be found in the commercial ADC grades known as RAV 7AT, Nouryset 200 and CR39. Merely from comparing the similar production processes of these two substances it is apparent that RAV 7AT and RAV 7NG are closely related to each other. Finally, the physical-chemical, toxicological and ecotoxicological properties of RAV 7NG and RAV 7AT are almost equal and as a result, read across is justified.
This endpoint is filled from data from one study in Selenastrum capricornutum (freshwater algae) (Maziarz, 1983a) and another in Skeletonema costatum (saltwater algae) (Maziarz,1983b). The no observable effect concentration (NOEC) for 'diallyl 2,2'-oxydiethyl dicarbonate' in Selenastrum capricornutum is 10 mg/L and in Skeletonema costatum 10µL/L (=11.48 mg/L).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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