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Diss Factsheets
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EC number: 801-694-5 | CAS number: 1392325-86-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The substance is hydrolytically stable in an OECD TG 111 study at pH 4, 7 and 9 at 25°C (DT50> 1 year).
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
Hydrolysis of the substance as a function of pH was examined in a study according to OECD TG 111 and in compliance with GLP (Envigo, 2016). Sample solutions were prepared in stoppered glass flasks by adding defined nominal concentrations to sterile buffer solutions with pH4, 7, and 9 and maintained at 50°C for a period of up to 240 hours. A co-solvent of acetonitrile was used to aid solubility. The solutions were shielded from light. In addition, a direct test at pH4, 7, and 9 was performed at 25°C for the duration of 30 days under otherwise the same conditions. Sample solutions were taken at various times, the concentration of each sample solution determined by HPLC (done for 2 components), and hydrolysis rates calculated. In the tests at 50°C data indicated the absence of any significant hydrolysis, i.e. less than 10% over a time period exceeding 120 hours at 50 °C. In the direct test at 25°C component 1 showed no evidence of any ongoing hydrolysis at pH4, 7 and 9. Component 2 also showed no evidence of any ongoing hydrolysis at pH7 and 9, but at pH4 the decrease in concentration versus time yielded a hydrolysis rate of 5.83E-04 h-1 which relates to a half-life of 49.5 days. Altogether, based on the results, the whole substance was considered to be hydrolytically stable.
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