Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 271-729-1 | CAS number: 68606-18-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility (WS 0.05 mg/L)
Key value for chemical safety assessment
Additional information
No experimental data evaluating the acute toxicity of Glycerides, mixed coco, decanoyl and octanoyl (CAS No. 68606-18-8) to aquatic invertebrates are available. Therefore, toxicity data from analogue category members, propane-1,2,3-triyl trisheptanoate (CAS No. 620-67-7) and Glycerides,C14-18 and C16-18 unsaturated, mono-, di- and tri- (CAS No. 91052-28-7), are used as read-across in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Glycerides, mixed coco, decanoyl and octanoyl is mainly a triglyceride formed by the combination of fatty acids of different C-chain lengths (C6 to C18 unsaturated) and glycerol. Propane-1,2,3-triyl trisheptanoate (CAS No. 620-67-7) is also a triglyceride with fatty acid chain length of C7. For Glycerides,C14-18 and C16-18 unsaturated, mono-, di- and tri- (CAS No. 91052-28-7) the triester content is lower than for the other two substances (up to 15%), with a predominant monoester content. The lower degree of esterification might have an effect in the bioavailability to aquatic organisms, due to a reduced size of the molecules, the potential to cross biological membranes is expected to increase. Therefore, Glycerides,C14-18 and C16-18 unsaturated, mono-, di- and tri- can be regarded as a worst-case read-across substance.The behaviour of these three substances in the water phase is expected to be very similar based on low water solubility values (< 0.05 mg/L for all) and log Pow (> 4). The two read-across substances cover the whole fatty acid C-chain range present in Glycerides, mixed coco, decanoyl and octanoyl. Therefore, they are considered to give a reliable indication of the toxicity of this substance to aquatic organisms, and the read-across is justified.
One study evaluating the acute toxicity of propane-1,2,3-tryil trisheptanoate (CAS No. 620-67-7) to aquatic invertebrates is available (Scholz, 1993). This test was conducted according to EU Method C.2, under GLP conditions. Daphnids were exposed for 48 hours to the test substance within a static water regime, at nominal concentrations ranging from 0.53 to 3.94 mg/L. No significant immobilization effects were observed in the treatment groups (only 1 immobilised daphnid at 3 out of 7 concentrations) nor in the controls (no immobilization) and therefore, the resulting EC50 (48 h) was found to be > 3.94 mg/L (measured concentration). The determination of measured test concentrations was performed by DOC (Dissolved Organic Carbon) analysis, which is more suitable for substances with higher water solubility. The high reported measured concentration (3.94 mg/L) despite the low water solubility of the substance (< 0.05 mg/L) shows that probably other constituents from the solution have been accounted for as test substance. Nevertheless, since no significant effects were observed it can be stated that no acute toxicity to aquatic invertebrates within the range of the water solubility of propane-1,2,3-tryil trisheptanoate is expected.The acute toxicity of Glycerides,C14-18 and C16-18 unsaturated, mono-, di- and tri- (CAS No. 91052-28-7)to aquatic invertebrates has been evaluated by Salinas (2013). This test was conducted according to OECD 202, under GLP conditions. Daphnia magna was exposed to the substance at a single loading rate of 100 mg/L (limit test) for 48 hours within a static water regime. At the end of the exposure period, no immobilization was observed. Therefore, the EL50 (48 h) was determined to be > 100 mg/L (nominal, loading rate).
Based on the results obtained for the structurally related category members (in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5), no acute toxicity of Glycerides, mixed coco, decanoyl and octanoyl (CAS No. 68606-18-8) to aquatic invertebrates up to the limit of its water solubility (< 0.05 mg/L) is expected.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.