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EC number: 212-058-6 | CAS number: 757-86-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Emergency and First Aid Procedures
Call a doctor (physician), clinic or hospital immediately. Explain that the victim has been exposed to an organophosphorus compound which can react with a range of compounds under formation of cholinesterase inhibitors - and describe his/her condition. Move the victim immediately from the area where MPEM is present.
If breathing has stopped, immediately start artificial respiration and maintain until a physician takes charge of the exposed person.
If swallowed and the exposed person is conscious, make him/her vomit quickly. Make the exposed person drink 1 or 2 glasses of water and induce vomiting by touching the back of the throat with a finger. Never give anything by mouth to an unconscious person. Get medical attention immediately.
In case of contact, immediately flush eyes or skin with plenty of water while removing contaminated clothing and shoes. See physician immediately.
Note to Physician
MPEM can react with a range of compounds under formation of cholinesterase inhibitors which affect the central and peripheral nervous systems producing respiratory depression.
Cholinesterase Inhibition - Treatment
Decontamination procedures such as whole body washing, gastric lavage and administration of activated charcoal are often required.
Antidote: If symptoms (see above) are present, administer atropine sulphate, which is often a lifesaving antidote, in large doses, TWO to FOUR mg intravenously or intramuscularly, as soon as possible. Repeat at 5 to 10 minute intervals until signs of atropinisation appear and maintain full atropinisation until all organophosphate is metabolised.
Obidoxime chloride (Toxogonin), alternatively pralidoxime chloride (2-PAM), may be administered as an adjunct to, but not a substitute for atropine sulphate. Treatment with oxime should be maintained as long as atropine sulphate is administered.
At first sign of pulmonary oedema the patient should be given supplementary oxygen and treated symptomatically.
Relapse can occur after initial improvement.
VERY CLOSE SUPERVISION OF THE PATIENT IS
INDICATED FOR AT LEAST 48 HOURS, DEPENDING ON THE SEVERITY OF POISONING.
Fire-fighting measures
Extinguishing Media and Procedure
Dry chemical or carbon dioxide for small fires, water spray or foam for large fires.
Use water spray to keep fire-exposed containers cool. Approach fire from upwind to avoid hazardous vapours and toxic decomposition products. Fight fire from protected location or maximum possible distance. Avoid heavy hose streams. Dike area to prevent water runoff. Firemen should wear self-contained breathing apparatus and protective clothing.
Hazardous Decomposition or Byproducts in a Fire
The essential breakdown products are dimethyl sulphide, sulphur dioxide, carbon monoxide, carbon dioxide and phosphorus pentoxide.
Accidental release measures
Steps to Be Taken in Case of Spill
Small liquid spills on the floor or other impervious surface should be swept up by means of an inert absorptive material such as hydrated lime, sawdust, Fuller’s earth or other absorbent clays. Scoop into proper containers and dispose of in accordance with the instructions provided under Disposal . Rinse area with soda lye.
Large liquid spills on the floor or other impervious surface should be contained or diked and then absorbed with an inert absorptive material such as hydrated lime, sawdust, Fuller’s earth or other absorbent clays. Collect the contaminated absorbent, place in a metal drum and dispose of in accordance with the instructions provided under Disposal. Rinse area with soda lye.
Large spills that soak into the ground should be dug up, placed in metal drums and disposed of in accordance with instructions provided under Disposal.
MPEM can be hydrolysed in water by heating and adjusting the pH (alkaline). MPEM may also be disposed of through proper incineration.
Handling and storage
In an industrial environment it is imperative to avoid all personal contact with the substance by handling and storing it only in closed systems with remote system control.
Adequate ventilation or local exhaust ventilation is required. The exhaust gases should be filtered or treated otherwise.
Avoid contact with eyes, skin or clothing. Avoid breathing vapour and avoid exposure of eyes to vapour as well.
Protect against moisture, air access and strong heat from sunshine or other source, e.g. fire.
MPEM is stable when stored in coated, unopened drums at temperatures not exceeding 20-25°C.
Storage at temperatures not exceeding 25°C is recommended. It should never be heated above 55°C. Local heating above this temperature should be avoided as well. Protect against strong heat from sunshine or other source, e.g. fire.
MPEM will decompose rapidly when heated to temperatures above 100°C, significantly increasing the risk of explosion.
The decomposition is dependent on time as well as temperature due to exothermic and autocatalytic reactions. The reactions involve rearrangements and polymerisation releasing volatile malodorous and inflammable compounds such as dimethyl sulphide.
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
When used in a closed system, personal protection equipment will not be required. The following is meant for other situations, when the use of a closed system is not possible, or when it is necessary to open the system, for example in the case of an accident. Consider the need to render equipment or piping systems non-hazardous before opening.
Wear chemical resistant gloves, such as barrier laminate, butyl rubber or nitrile rubber. The breakthrough times of these materials for this product are unknown. Generally, however, the use of protective gloves will give only partial protection against dermal exposure. Small tears in the gloves and cross-contamination can easily occur. It is recommended to shift the gloves frequently and to limit the work to be done manually.
In case of insufficient ventilation, workers should put on officially approved respiratory protection equipment with a combination filter type against acids and including particle filter and wear appropriate chemical resistant clothing to prevent skin contact.
Stability and reactivity
MPEM is stable when stored in coated, unopened drums at temperatures not exceeding 20-25°C.
Storage at temperatures not exceeding 25°C is recommended. It should never be heated above 55°C. Local heating above this temperature should be avoided as well. Protect against strong heat from sunshine or other source, e.g. fire.
MPEM will decompose rapidly when heated to temperatures above 100°C, significantly increasing the risk of explosion.
The decomposition is dependent on time as well as temperature due to exothermic and autocatalytic reactions. The reactions involve rearrangements and polymerisation releasing volatile malodorous and inflammable compounds such as dimethyl sulphide.
Disposal considerations
Waste Disposal Method
Spill and waste disposal procedures in accordance with state and local regulations must be followed.
Do not contaminate water, food or feed by storage and disposal.
Container Disposal
Triple rinse (or equivalent). Then offer for recycling or reconditioning, or puncture and dispose of in a sanitary landfill. However, procedures in accordance with state and local authorities must be followed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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