Registration Dossier
Registration Dossier
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EC number: 254-372-6 | CAS number: 39236-46-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a study considered to give a reliable 96h LC0 value (but unreliable for LC50 determination due to low dissolved oxygen levels), 96h exposure at a nominal concentration of 220 mg/l caused no mortality of bluegill sunfish: accordingly a 96h LC50 value of >220 mg/l is concluded. This evidence of low acute toxicity to fish is compatible with results obtained in fish acute toxicity studies using the close chemical analogue (and similar formaldehyde donor) Diazolidinylurea.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 220 mg/L
Additional information
Four reliable studies of acute toxicity to fish are available for the close analogue diazolidinylurea, using two fish species. In rainbow trout, no significant adverse effects were seen at the maximum concentrations tested (100 mg/l nominal or 150 mg/l mean measured). Using bluegills, 10% mortality was reported at 100 mg/l (nominal) plus 55% mortality at 116 mg/l (mean measured). Based on these results a 96h LC50 between 100 and 116 mg/l was concluded for diazolidinylurea: whilst this is a little lower than the 96h LC50 value of >220 mg/l concluded for the registered substance, it can be concluded that both substances show low acute toxicity to fish.
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