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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 938-820-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
- the bacterial reverse mutation test (according to OECD guideline 471): The test was carried out in two versions, a standard plate test (experiment 1) and a preincubation assay (experiment 2). Both experiments were conducted with and without metabolic activation (S9 mix obtained from rats treated with phenobarbital and beta-naphthoflavone) in the following strains: TA 1535, TA 100, TA 1537, TA 98 and E. coli WP2 uvrA. The test substance was applied in doses of 33 -10 000 ug/plate. The test substance did not lead to a relevant increase in the number of revertant colonies in any of the experiments.
- the gene mutation assay in chinese hamster V79 cells (HPRT test, according to OECD guideline 476): The test was conducted with and without metabolic activation according to the following scheme: Experiment 1: 4 hours treatment +/-S9; experiment 2: 4 hours treatment +S9, 24 hours -S9. The test substance was applied in doses ranging from 26.6 ug/ml to 850 ug/ml, except for 4 hours treatment -S9 in experiment 1 (53.1 -1700 ug/ml). The test substance did not induce a dose-dependent increase in mutation frequency.
- the chromosome aberration test in chinese hamster V79 cells (according to OECD guideline 473): The test was conducted with and without a recovery phase after treatment with the test substance (experiments 1 and 2, respectively), each with and without metabolic activation. The test substance was applied in doses ranging from 26.6 to 6800 ug/ml. No relevant increase in the number of cells carrying structural or numeric chromosme aberrations was observed
Lactamoil 70% was tested for genotoxicity in three different in vitro test systems:
Together, the results of these tests indicate that Lactamoil 70% is not genotoxic in vitro.
Short description of key information:
Lactamoil 70% was tested in 3 different in vitro genotoxicity tests assessing different endpoints and showed no mutagenic or clastogenic activity.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
No indication of a genotoxic potential was observed. Thus, no classification is required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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