Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-055-9 | CAS number: 298-06-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1997
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study is a publication with detailed description of the method used.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Kinetics and Mechanism of Hydrolysis of Di-Ethyl Dithiophosphate in Acid Media
- Author:
- Patil, R. et al
- Year:
- 1 997
- Bibliographic source:
- Asian Journal of Chemistry, Vol. 9, No. 3, 407-410
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Deviations:
- not applicable
- Principles of method if other than guideline:
- Reactions using diethyl dithiophosphate were carried out at 98°C employing 5E-04 mol/dm3 solution of diester which was subsequently followed by the Allen's modified method of colorimetric estimation of organic phosphate in aqueous media maintaining constant ionic strength by means of HCl and NaCl.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- O,O-diethyl hydrogen phosphorodithioate
- EC Number:
- 206-055-9
- EC Name:
- O,O-diethyl hydrogen phosphorodithioate
- Cas Number:
- 298-06-6
- Molecular formula:
- C4H11O2PS2
- IUPAC Name:
- O,O-diethyl sulfanylphosphonothioate
- Details on test material:
- - Name of test material (as cited in study report): diethyl dithiophosphate
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- not specified
- Estimation method (if used):
- Not applicable
- Number of replicates:
- Not applicable
- Positive controls:
- not specified
- Negative controls:
- not specified
- Statistical methods:
- Not applicable
Results and discussion
- Transformation products:
- not specified
- Details on hydrolysis and appearance of transformation product(s):
- The rate of hydrolysis of diethyl dithiophosphate was studied in HCl (0.1 - 7 mol/dm3). The pseudo first order rate constants were determined from which it is clear that the rste of reaction increases up to 4 mol/dm3 HCl but further increase in acid molarity decreases the rate as it can be attributed to the complete conversion of the ester (basic) molecule into their respective conjugate acid species with the lowering of concentration of a nucleoplhile (water), which plays its role in rate determining step of bimolecular hydrolytic reaction.
- Other kinetic parameters:
- In order to determine whether or not there is an effect of ionic strength or presence of acid catalysis, kinetic runs were made at three different ionic strength (1.0, 2.0 and 3.0) which were maintained by adequate mixture of NaCl and HCl. Hydrolysis at each ionic strength is represented by a linear curve that makes a positive slope. From the study of ionic strength, the total rates contributed by conjugate acid and neutral were calculated.
- Details on results:
- Arrhenius parameters were determined for the hydrolysis at 3.0 and 5.0 mol/dm3 HCl. The magnitude of these parameters falls in the range of bimolecular reaction. Bimolecular nature of reaction is further supported by additional parameters suggesting that water involved as a proton transfer agent is the rate determining step. Comparative kinetic data also support the bimolecular nature of hydrolysis involving attack of water molecule on phosphorous of the diester involving P-O bond fission.
Any other information on results incl. tables
No other information.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- A bimolecular nature of hydrolysis of diethyl dithiophosphate is proposed.
- Executive summary:
Investigation of the hydrolysis of diethyl dithiophosphate was carried out by using Allen's modified method of colorimetry, in aqueous solution medium from 0.1 to 7.0 mol/dm3 HCl at 98°C.
Based on the results obtained, a bimolecular nature of hydrolysis involving attack of water molecule is proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.