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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 1994
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The study and data are well documented and scientifically acceptable.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
ISO DIS 9408 (Ultimate Aerobic Biodegradability - Method by Determining the Oxygen Demand in a Closed Respirometer)
Version / remarks:
and OECD 301F
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Iohexol
EC Number:
266-164-2
EC Name:
Iohexol
Cas Number:
66108-95-0
Molecular formula:
C19H26I3N3O9
IUPAC Name:
5-[acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, adapted
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
100 mg/L

Results and discussion

% Degradation
Parameter:
% degradation (DOC removal)
Value:
0
Sampling time:
28 d

Applicant's summary and conclusion

Interpretation of results:
not inherently biodegradable
Conclusions:
The result classify as "not readily biodegradable" according to the OECD criteria, which require a DOC removal of 70% in 28 days for classification as "readily biodegradable"