Registration Dossier
Registration Dossier
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EC number: 224-207-2 | CAS number: 4246-51-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to aquatic algae.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 31.3 mg/L
Additional information
An algae growth inhibition study was performed with 3,3'-oxybis(ethyleneoxy)bis(propylamine) according to the German Industrial Standard DIN 38412, Part 9 using Desmodesmus subspicatus. The test item concentrations were not analytically verified. However, it is assumed that the test concentrations remained stable over the exposure period based on a high water solubility, a low potential to evaporate into air (Henry’s Law constant < 1 Pa*mol/cm³) and a low potential for adsorption (log Kow and log Koc < 3).
The inhibitory effect on algal growth was studied on not pH-adjusted test solutions. In parallel, three treatment levels were tested after pH-adjustment. While the inhibition of the higher test concentrations (125 and 500 mg/L) were on a similar level as the not pH-adjusted solutions, the lowest test concentration (15.6 mg/L) showed a higher inhibitory effect after pH-adjustment (36% compared to 8%). The results from the pH-adjusted test should be regarded as indicative values since a reduced number of test solutions were tested (3 instead of 5) and the dilution factor between treatment levels does not conform with the guideline.
The ecotoxicologial endpoints were re-calculated using the program ToxRatPro (v2.09). The study is considered valid. Based on growth rate and not pH-adjusted test solutions, the 72 -h ErC50 is > 500 mg/L, the 72 -h ErC10 is 31.3 mg/L and the 72 -h NOEC is 15.6 mg/L (nominal; BASF AG, 1990; report no. 2/0505/89).
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