(E)-1,2-difluoroethylene

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental start date: 26 March 2020; Experimental completion date: 28 April 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)

Qualifier:

according to guideline

Guideline:

EU Method A.8 (Partition Coefficient - Shake Flask Method)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Partition coefficient type:

octanol-water

Specific details on test material used for the study:

Identity: TKN1
Batch number: N1200213
Physical state/appearance: Colourless gas
Purity: 100%
Storage conditions: Room temperature
Expiry date: 10 August 2022

Analytical method:

gas chromatography

Key result

Type:

log Pow

Partition coefficient:

0.86

Temp.:

20 °C

pH:

>= 6.2 - <= 6.3

Details on results:

A summary of the test showed a measured log10Pow value of 0.86 (equivalent Pow = 7.2).

Acceptable mean recoveries of approximately 81, 84, 78 and 77% of TKN1 from fortified samples were achieved at the LOQ and high levels in water and n-octanol, respectively.

Determination of the Partition Coefficient of TKN1

  

Sample	A	B	C	D	E	F
n-octanol volume (mL)	10	10	13	13	6.5	6.5
Test substance in n-octanol (mg/L)	411.6	468.2	370.4	389.7	550.3	565.2
Total test substance in n-octanol (mg)	4120	4680	4820	5070	3580	3670
Aqueous volume (mL)	10	10	6.5	6.5	13	13
Test substance in aqueous phase (mg/L)	61.24	63.96	53.16	52.11	75.70	76.46
Total test substance in aqueous phase (mg)	612	640	346	339	984	994
Total test substance added (mg)	5720	5720	5720	5720	5720	5720
Total test substance recovered (mg)	4730	5320	5160	5400	4560	4670
pH of aqueous phase after partition	6.3	6.3	6.2	6.3	6.3	6.3
Pow	6.72	7.32	6.97	7.48	7.27	7.39
log10Pow	0.827	0.865	0.843	0.874	0.862	0.869

 

Mean log₁₀P_ow= 0.86 ± 0.02

Equivalent P_ow= 7.2

Conclusions:

The test item, TKN1, was found to have a log10Pow value of 0.9.

Executive summary:

TKN1 was found to have a log₁₀P_owvalue of 0.9, following a procedure designed to be compatible with OECD 107 and EC Method A.8

Description of key information

TKN1 was found to have a log₁₀P_ow value of 0.9, following a procedure designed to be compatible with OECD 107 and EC Method A.8

Key value for chemical safety assessment

Log Kow (Log Pow):

0.9

at the temperature of:

20 °C