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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Endpoint:
bioaccumulation in aquatic species: fish
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance has a low potential for bioaccumulation based on log Kow <=3
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING
Study scientifically not necessary / other information available: In accordance with Column 2 of REACH Annex IX, the study need not to be conducted if the substance has a low potential for bioaccumulation. The test substance has a predicted log Kow<3.
Reason / purpose:
data waiving: supporting information
Endpoint:
bioaccumulation in sediment species, other
Remarks:
not determined
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
Internationally accepted calculation method, EPI-Suite EPA (USA).
The test substance VL3 hydrolyses to ethyl lactate and ethenylsilanetriol.
Reason / purpose:
reference to other study
Qualifier:
according to
Guideline:
other: REACH Guidance on QSARs
GLP compliance:
no
Remarks:
not applicable to QSAR models
Specific details on test material used for the study:
C=C[Si](O)(O)O
Type:
BCF
Value:
ca. 3.162 L/kg
Basis:
other: wet-wt
Calculation basis:
other: regression-based method
Remarks on result:
other: EPI-Suite estimated value
Validity criteria fulfilled:
not applicable
Conclusions:
The estimated bioaccumulation of the ethenylsilanetriol expressed as BCF is 3.162 L/kg based on the estimated log Kow of -2.01 ( EPI-Suite, BCFBAF v3.01).
Executive summary:

The bioaccumulation in aquatic species of ethenylsilanetriol was determined by calculation. This calculation was performed by the computer program from US-EPA (EPI-Suite software BCFBAF v3.01). The estimated bioaccumulation expressed as BCF is 3.162 L/kg based on the estimated log Kow of -2.01.

Endpoint:
bioaccumulation in aquatic species, other
Remarks:
not determined
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
Internationally accepted calculation method, EPI-Suite EPA (USA).
Qualifier:
according to
Guideline:
other: REACH Guidance on QSARs
GLP compliance:
no
Remarks:
not applicable to QSAR models
Specific details on test material used for the study:
SMILES : CC(O[Si](OC(C)C(=O)OCC)(OC(C)C(=O)OCC)C=C)C(=O)OCC
Key result
Type:
BCF
Value:
ca. 2.225 L/kg
Basis:
other: wet-wt
Calculation basis:
other: regression-based method
Remarks on result:
other: EPI-Suite estimated value
Validity criteria fulfilled:
not applicable
Conclusions:
The estimated bioaccumulation of VL3 expressed as BCF is 2.225 L/kg based on the estimated log Kow of 1.03 ( EPI-Suite, BCFBAF v3.01).
Executive summary:

The bioaccumulation in aquatic species of the test substance was determined by calculation. This calculation was performed by the computer program from US-EPA (EPI-Suite software BCFBAF v3.01). The estimated bioaccumulation expressed as BCF is 2.225 L/kg based on the estimated log Kow of 1.03.

Endpoint:
bioaccumulation in aquatic species, other
Remarks:
not determined
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
Internationally accepted calculation method, EPI-Suite EPA (USA).
The test substance VL3 hydrolyses to ethyl lactate and ethenylsilanetriol.
Reason / purpose:
reference to other study
Qualifier:
according to
Guideline:
other: REACH Guidance on QSARs
GLP compliance:
no
Remarks:
not applicable to QSAR models
Specific details on test material used for the study:
SMILES : O=C(OCC)C(O)C
Key result
Type:
BCF
Value:
ca. 3.162 L/kg
Basis:
other: wet-wt
Calculation basis:
other: regression-based method
Remarks on result:
other: EPI-Suite estimated value
Validity criteria fulfilled:
not applicable
Conclusions:
The estimated bioaccumulation of ethyl lactate expressed as BCF is 3.162 L/kg based on the estimated log Kow of -0.18 ( EPI-Suite, BCFBAF v3.01).
Executive summary:

The bioaccumulation in aquatic species of ethyl lactate was determined by calculation. This calculation was performed by the computer program from US-EPA (EPI-Suite software BCFBAF v3.01). The estimated bioaccumulation expressed as BCF is 3.162 L/kg based on the estimated log Kow of -0.18.

Description of key information

Data waiving: Study scientifically not necessary / other information available: In accordance with Column 2 of REACH Annex IX, the study need not to be conducted if the substance has a low potential for bioaccumulation. The test substance has a predicted log Kow < 3.

Supporting study: The estimated bioaccumulation of VL3 expressed as BCF is 2.225 L/kg based on the log Kow 1.03 ( EPI-Suite, BCFBAF v3.01).

The test substance VL3 hydrolyses to ethyl lactate and ethenylsilanetriol.

Supporting study: The estimated bioaccumulation of ethyl lactate expressed as BCF is 3.162 L/kg based on the estimated log Kow of -0.18 ( EPI-Suite, BCFBAF v3.01).

Supporting study: The estimated bioaccumulation of the ethenylsilanetriol expressed as BCF is 3.162 L/kg based on the estimated log Kow of -2.01 ( EPI-Suite, BCFBAF v3.01).

Key value for chemical safety assessment

BCF (aquatic species):
2.225 L/kg ww

Additional information