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EC number: 946-383-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15. May 2018 to 17. May 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- OECD Guideline for the Testing of Chemicals No. 102 dated 27. July 1995 “Melting Point / Melting Range"
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- Regulation (EC) No 440/2008 of 30 May 2008, published on 31. May 2008, Method A.1, “Melting/Freezing Temperature”
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Specific details on test material used for the study:
- No further details specified in the study report.
- Key result
- Melting / freezing pt.:
- >= -57.61 - < -40.53 °C
- Decomposition:
- no
- Sublimation:
- no
- Remarks on result:
- other: Atm. press. not specified
- Conclusions:
- The determination of the melting point of Trixene AS was performed via DSC (differential scanning calorimetry)
In the first and second DSC measurements a flat and broad exothermic event during the cooling down phase was detected. In the third no event could be clearly detected.
The exothermic event can be identified as freezing range (-54.76°C - -63.27°C) (evaluated with the event marker function).
In the heating up phase, a flat and broad endothermic event was detected in every measurement. This endothermic Event can be identified as melting range (-57.61°C - -40.53°C) (evaluated with the event marker function).
No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid. - Executive summary:
Determination of the melting point of Trixene AS according to OECD 102 resp. EU A.1
Findings and Results:
The melting point was determined via DSC (differential scanning calorimetry)
Referring to the pre-test the melting point should be between -20 °C and -80 °C.
In the first and second DSC measurements a flat and broad exothermic event during the cooling down phase was detected. In the third no event could be clearly detected.
The exothermic event can be identified as freezing range (-54.76°C - -63.27°C) (evaluated with the event marker function).
In the heating up phase, a flat and broad endothermic event was detected in every measurement. This endothermic event can be identified as melting range (-57.61°C - -40.53°C) (evaluated with the event marker function).
No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.
Reference
Pre-Test
Values Pre-Test
Room temperature |
4.8 °C |
-19.5 °C |
-80 °C |
Clear slightly green-ish, viscous liquid |
Same as room temperature |
More viscous than at room temperature, nor flowable anymore |
Solid like ice |
Calibration
Values DSC Indium
Expected Melting point |
Measured Melting point |
Expected Energy |
Measured Energy |
Assessment |
156.6 ± 1.0 °C |
156.55 °C (onset) |
28.45 ± 1.0 J/g |
28.60 J/g |
OK |
The measurement of indium after calibration met the validity criteria.
DSC Measurement of the Test Item
First determination
Values DSC Test Item first determination
|
Temperature [°C] |
Energy |
Freezing Point |
-55.07 (Onset) Range (Event marker) -54.76 to -62.61 |
-0.18 [J/g] (the minus symbol is stated for the energy of exothermic event) |
Melting Point |
-53.11 (Onset) Range (Event marker) -57.20 to -40.69 |
1.90 [J/g] |
Repetition second determination
Values DSC Test Item second determination
|
Temperature [°C] |
Energy |
Freezing Point |
-55.57 (Onset) Range (Event marker) -55.29 to -63.27 |
-0.73 [J/g] (the minus symbol is stated for the energy of exothermic event) |
Melting Point |
-51.90 (Onset) Range (Event marker) -54.18 to -40.53 |
1.63 [J/g] |
The deviation between the first and second determination was too high (> 0.5 K) and the peaks of two determinations were different; therefore, a third measurement was performed with a new crucible.
Third determination
Values DSC Test Item third determination
|
Temperature [°C] |
Energy |
Freezing Point |
No event visible |
No event visible |
Melting Point |
-53.55 (Onset) Range (Event marker) -57.61 to -42.55 |
1.72 [J/g]
4.70 mW – 5.44 mW |
Observations
Values Observations
|
Mass test item |
Mass crucible (before measurement): |
Mass crucible (after measurement): |
Observations |
First Measurement |
4.93 mg |
50.10 mg |
50.10 mg |
The crucible was optically unchanged after measurement |
Repetition Second Measurement |
4.93 mg |
50.10 mg |
50.10 mg |
The crucible was optically unchanged after measurement |
Third Measurement |
5.10 mg |
50.44 mg |
50.44 mg |
The crucible was optically unchanged after measurement |
Interpretation
In the first and second DSC measurements a flat and broad exothermic event during the cooling down phase was detected.
The exothermic event can be identified as freezing range (-54.76°C - -63.27°C) (evaluated with the event marker function).
In the heating up phase, a flat and broad endothermic event was detected in every measurement. This endothermic Event can be identified as melting range (-57.61°C - -40.53°C) (evaluated with the event marker function).
Description of key information
melting range (-57.61°C - -40.53°C)
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -40.53 °C
Additional information
The melting point was determined via DSC (differential scanning calorimetry)
Referring to the pre-test the melting point should be between -20 °C and -80 °C.
In the first and second DSC measurements a flat and broad exothermic event during the cooling down phase was detected. In the third no event could be clearly detected.
The exothermic event can be identified as freezing range (-54.76°C - -63.27°C) (evaluated with the event marker function).
In the heating up phase, a flat and broad endothermic event was detected in every measurement. This endothermic event can be identified as melting range (-57.61°C - -40.53°C) (evaluated with the event marker function).
No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.
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