Registration Dossier
Registration Dossier
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EC number: 244-846-0 | CAS number: 22221-10-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Aquatic toxicity studies of 2-ethylhexanoic acid, copper salt are not available. Thus, read-across to the assessment entities soluble copper substances and
2-ethylhexanoic acid is applied since the ions of 2-ethylhexanoic acid, copper salt determine its fate and toxicity in the environment. Reliable studies indicate that the moiety of ecotoloxicological concern are copper cations. Regarding copper, a 30-d NOEC of 0.23 mg dissolved Cu/L (inhibition of total respiration / respiration rate) was determined for microorganisms based on a weight-of-evidence approach and five studies. Data for naphthenic acid point to low toxic potential to aquatic microorganisms since an inhibition was not observed up to and at 100 mg/L in a biodegradation test. For 2-ethylhexanoate, EC10 (71.7 mg/L) and EC50 (112.1 mg/L) values were derived after 17 hours of exposure of Pseudomonas putida. Thus, 2-ethylhexanoic acid, copper salt appears to have potential for toxicity to aquatic microorganisms.
Key value for chemical safety assessment
Additional information
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