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Diss Factsheets
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EC number: 201-744-0 | CAS number: 87-41-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- 73.27
- Remarks on result:
- other: Study was performed without adjustment of atm. pressure.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Secondary literature source no data about the method was available.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Melting / freezing pt.:
- 70 - 75 °C
- Remarks on result:
- other: Value from generally accepted authoritative handbook. No data available for atm. pressure.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 18 -19 Jan 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 113 Screening test for thermal stability and stability in air
- Qualifier:
- according to guideline
- Guideline:
- other: EU Method A.14 (Explosive properties)
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
- Melting / freezing pt.:
- ca. 73.76 °C
- Remarks on result:
- other: Two DSC measurements in closed glass crucibles with the test item showed an endothermal effect in the temperature range of 60-85 °C.
Referenceopen allclose all
The DSC measurement was conducted for a study according to A.14. (closed glass crucible) and showed a melting point at approximately 73.76 °C.
Description of key information
The value for the melting point was determined in an experimental study performed equivalent or similar to OECD 102 (BASF AG, 1989). The boiling point of phthalide was found to be 73.27 °C.
In a second experimental study performed according to OECD 113, differential scanning calorimetry (DSC, closed crucible) measurements showed a melting point at approximately 73.76 °C which is in line with other reported values (Winkler, 2018).
In addition, the melting point of phthalide was reported to be in the range of 70-75 °C according to the Knovel Critical Tables (2nd Edition).
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 73 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.