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EC number: 208-634-1 | CAS number: 536-45-8
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 June 2017 to 28 July 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 23 March 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 30 May 2008
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: estimation method (Grain-Watson) based on the lowest possible boiling point which was determined by DSC.
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- <= 0 Pa
- Test no.:
- #2
- Temp.:
- 50 °C
- Vapour pressure:
- <= 0.012 Pa
- Conclusions:
- Vapour pressure is ≤ 4.0x10-4 Pa at 20 °C and ≤ 1.2x10 -2 Pa at 50 °C (EU Method A.4, Grain Watson estimation)
Reference
Final Result
The test item (Sodium Anisate) has a vapour pressure of ≤ 4.0x10-9 atm (≤ 4.0x10-4 Pa; ≤ 4.0x10-6 mbar) at 20 °C and of ≤ 1.2x10-7 atm (≤ 1.2x10-2 Pa; ≤ 1.2x10-4mbar) at 50 °C (the calculation is based on the lowest possible boiling temperature) (Grain Watson estimation). The experimentally determined vapour pressure of the test item at 20 °C of << 1 mbar is not in the recommended range of 1 to 1000 mbar for DSC-measurements. Therefore an estimation procedure according the test method A.4 as described in the Council Regulation (EC) no 440/2008 of 30 may 2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council o the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) similar to the test method OECD Guideline 104 (see Appndix 1, Estimation Method, newest version (Robert S. Boethling, Donald Mackay, Handbook of Property Estimation MEthods for Chemicals, Lewis Pblishers, year of publication 200, Cap. 3 - Vapour Pressure, Grain-Watson Method, p- 53 - 65) was used.
This method is applied for vapour pressures between 10E03 to 10E-07 mbar.
This deviates from the older version published in the test method A.4. It was used due to the differentiation between solids and liquids, which results in a more precise estimate.
Description of key information
Vapour pressure is ≤ 4.0x10-4 Pa at 20 °C and ≤ 1.2x10 -2 Pa at 50 °C (EU Method A.4, Grain Watson estimation).
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
