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EC number: 274-417-3 | CAS number: 70210-20-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 7 December 2017 - 15 January 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- yes
- Remarks:
- refer to 'Any other information on materials and methods' section.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Deviations:
- yes
- Remarks:
- refer to 'Any other information on materials and methods' section.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
- Deviations:
- yes
- Remarks:
- refer to 'Any other information on materials and methods' section.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: RR-24-001
- Expiration date of the lot/batch: July 1, 2022
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: at room temperature (20 +/- 5°C) in the dark - Analytical method:
- liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- < -3.26
- Temp.:
- 20 °C
- pH:
- ca. 6.5
- Details on results:
- Three volume ratios (water / n-octanol) have been tested using two replicates for each volume ratio. From data of each run, a partition coefficient was calculated. The six log Pow values were determined within a range of +/- 0.3 log units. As the differences between the three volume ratios was less than the given +/- 0.3 log units, the study was considered to be valid.
- Conclusions:
- The log Pow value of Reactive Red 24 was determined to be < -3.26 using the shake flask method at 20°C.
- Executive summary:
The partition coefficient was calculated based on the results of the analytical determination. The test item content was determined by HPLC/VIS. The log Pow was calculated for each of the six runs (two replicates of three volume ratios). The difference between the three different test variants was less than the given +/- 0.3 log units. Therefore, the study can be considered to be valid. According to this study the logarithmic partition coefficient (n-octanol/water) of the test item was determined to be < -3.26 using the shake flask method at 20°C.
Reference
Description of key information
The log Pow value of Reactive Red 24 was determined to be < -3.26 using the shake flask method at 20°C.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -3.26
- at the temperature of:
- 20 °C
Additional information
The partition coefficient was calculated based on the results of the analytical determination. The test item content was determined by HPLC/VIS. The log Pow was calculated for each of the six runs (two replicates of three volume ratios). The difference between the three different test variants was less than the given +/- 0.3 log units. Therefore, the study can be considered to be valid. According to this study the logarithmic partition coefficient (n-octanol/water) of the test item was determined to be < -3.26 using the shake flask method at 20°C.
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