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Diss Factsheets
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EC number: 203-951-1 | CAS number: 112-25-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of an acute toxicity test with Pimephales promelas (fathead minnow ) to ethylene glycol hexyl ether (EGHE), a 96-hr LC50 of 140 mg/L was reported.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 140 mg/L
Additional information
One key study along with three supporting studies were identified for ethylene glycol hexyl ether (EGHE) acute toxicity to fish. In a 96 -hour Static Acute Fish test (identified as the key study) with fathead minnows (Pimephales promelas), conducted in accordance with OECD TG 203, EPA OTS 797.1400 and ASTM guidelines, the 96 hour LC50 value of EGHE was found to be 140 mg/L, with 95% confidence limits that ranged from 130 -140 mg/L and an NOEC value of 40 mg/L. In another 96 -hour Static Acute Fish test on fathead minnows (Pimephales promelas), conducted in accordance with the EPA and ASTM guidelines, the 96 hour LC50 value of EGHE was also reported to be 140 mg/L. Similarly, in an additional 96 -hour Static Acute Fish test on fathead minnows (Pimephales promelas), conducted in accordance with the EPA and ASTM guidelines, the 96 hour LC50 value of EGHE was found to be 139.5 mg/L. A fourth supporting study, following OECD guidelines (OECD 203) and GLPs, reported a 96 hour LC50 value for zebrafish as >100 - 220 mg/L.
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