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Diss Factsheets
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EC number: 221-717-7 | CAS number: 3209-22-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Principles of method if other than guideline:
- acute toxicity of 2,3-dichloronitrobenzene to Drosophila melanogaster was tested by injection of a solution the test substance into the fly and by feeding of a solution of the test substance
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- yes
- Details on preparation and application of test substrate:
- - a stock solution was prepared in 0.6-3% of ethanol in water
- in case of the injection test the stock solution was diluted with a 0.7% solution of sodium chloride in water
- in case of the feeding test the stock solution was diluted with a 5% solution of saccharose in water - Test organisms (species):
- Drosophila melanogaster
- Animal group:
- Diptera (fruit fly (small))
- Details on test organisms:
- - only male flies were tested
- Nominal and measured concentrations:
- - in both experiments (injection + feeding) a nominal concentration of 20 mg/l was tested
- Conclusions:
- acute toxicity of 2,3-dichloronitrobenzene to Drosophila melanogaster was tested by injection of a solution the test substance into the fly and by feeding of a solution of the test substance. Only male flies were tested. A LC 50 = 20 mg/L was derived (sterility).
- Executive summary:
acute toxicity of 2,3-dichloronitrobenzene to Drosophila melanogaster was tested by injection of a solution the test substance into the fly and by feeding of a solution of the test substance. Only male flies were tested. A LC 50 = 20 mg/L was derived (sterility).
Reference
Injection test (24 hours)
LC11 = 20 mg/l
Sterility rate: 1%
Feeding test (72 hours)
LC30 = 20 mg/l
Sterility rate: 2%
Description of key information
For transported isolated intermediates according to Reach, Annex XVIII, this endpoint is not a data requirement. However, data is available for this endpoint and is thus reported under the guidance of "all available data".
Acute toxicity of 2,3-dichloronitrobenzene to Drosophila melanogaster was tested by injection of a solution the test substance into the fly and by feeding of a solution of the test substance. Only male flies were tested. A LC 50 = 20 mg/L was derived (sterility).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.