Registration Dossier
Registration Dossier
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EC number: 615-749-4 | CAS number: 72291-30-6
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study without restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 310 (Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-cyano-2-methyl-propanoic acid methyl ester
- EC Number:
- 615-749-4
- Cas Number:
- 72291-30-6
- Molecular formula:
- C6 H9 N O2
- IUPAC Name:
- 2-cyano-2-methyl-propanoic acid methyl ester
- Details on test material:
- - Name of test material (as cited in study report): 2-Cyano-2-methyl-propanoic acid-methyl ester
- Analytical purity: 99.8 % coreected peak area
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Activated sludge from a laboratory wastewater plant treating municipal sewage .
- Initial cell/biomass concentration: Concentration of dry substance 4 mg/I . - Duration of test (contact time):
- 49 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Initial conc.:
- 35 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- inorg. C analysis
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to guideline
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (inorg. C analysis)
- Value:
- 10 - 20
- Sampling time:
- 28 d
- Parameter:
- % degradation (inorg. C analysis)
- Value:
- 20 - 30
- Sampling time:
- 49 d
- Details on results:
- Kinetic of test substance (in %):
= 15 after 7 day(s)
= 18 after 14 day(s)
= 19 after 21 day(s)
= 20 after 35 day(s)
= 22 after 49 day(s)
Kinetic of control substance (in %):
= 81 after 7 day(s)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other:
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