α-methylcyclohexanepropanol

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015-10-28 to 2015-10-29

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: OECD Test Guideline 113 (1981): Screening Test for Thermal Stability and Stability in Air

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996, applies to result

Deviations:

no

GLP compliance:

no

Remarks:

The study was conducted under supervision of a quality assurance unit which had ensured e.g instrumentation validation, reagent/materials certification, analyst certification and providing standard operating procedures.

Type of method:

dynamic method

Key result

Temp.:

20 °C

Vapour pressure:

0.73 hPa

Key result

Temp.:

25 °C

Vapour pressure:

0.95 hPa

Key result

Temp.:

50 °C

Vapour pressure:

3.2 hPa

Test no.:

#1

Temp.:

94.8 °C

Vapour pressure:

19.5 hPa

Test no.:

#2

Temp.:

118.8 °C

Vapour pressure:

39.7 hPa

Test no.:

#3

Temp.:

126.8 °C

Vapour pressure:

49.5 hPa

Test no.:

#4

Temp.:

134.7 °C

Vapour pressure:

62 hPa

Test no.:

#5

Temp.:

140.5 °C

Vapour pressure:

78.5 hPa

Test no.:

#6

Temp.:

146.1 °C

Vapour pressure:

93.5 hPa

Test no.:

#7

Temp.:

136.9 °C

Vapour pressure:

68.9 hPa

Test no.:

#8

Temp.:

129.5 °C

Vapour pressure:

55 hPa

Test no.:

#9

Temp.:

114.5 °C

Vapour pressure:

34.9 hPa

Pre test: Thermal Stability

The test item in a closed glass crucible showed a small exothermic effect in the temperature range of 120 - 170 °C, with an energy of – 10 J/g.

 

Main test: Dynamic method - Vapour-liquid equilibrium (VLE)

The vapour pressure was measured in the temperature range of 94.8 to 146.1 °C. 

From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation was derived by regression (Microsoft Excel) of the data points to

 

A = 8.7920

B = -2031.68

C = 273.15

 

The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation (EC) No 440/2008 Method A.4.

Conclusions:

The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.

Executive summary:

A study was conducted according to OECD TG 104 determine the vapour pressure of the test item using the dynamic method (VLE). A vapour pressure curve with 9 data points was measured over a temperature range between 94.8 to 146.1 °C. From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation was derived and the vapour pressure of the test item as calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation (EC) No 440/2008 Method A.4. The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.

Description of key information

The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.

Key value for chemical safety assessment

Vapour pressure:

0.73 hPa

at the temperature of:

20 °C

Additional information

A study was conducted according to OECD TG 104 to determine the vapour pressure of the test item using the dynamic method (VLE). A vapour pressure curve with 9 data points was measured over a temperature range between 94.8 to 146.1 °C. The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C. The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.