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EC number: 235-715-9 | CAS number: 12607-70-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Additional information on environmental fate and behaviour
Administrative data
- Endpoint:
- additional information on environmental fate and behaviour
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: OECD 29: Transformation/Dissolution of Metals and Metal Compounds in Aqueous Media
- GLP compliance:
- no
Test material
- Reference substance name:
- [carbonato(2-)]tetrahydroxytrinickel
- EC Number:
- 235-715-9
- EC Name:
- [carbonato(2-)]tetrahydroxytrinickel
- Cas Number:
- 12607-70-4
- Molecular formula:
- Ni3(OH)4CO3
- IUPAC Name:
- trinickel monocarbonate tetrahydroxide
Constituent 1
Results and discussion
Any other information on results incl. tables
Among the five screening tests at pH 6, the average value of Ni(aq) was 34.5 ± 10.7 mg/L while the maximum and minimum average values were 45.1 and 22.1 mg/L, respectively. The higher end of this range approaches the calculated concentration of 51.9 mg/L for the complete dissolution of pure NiCO3. The variability among the five flasks, expressed as a percentage of the standard deviation divided by the average value of Ni(aq), was 28%. This variability exceeded the anticipated between-vessel variation of 20%, possibly due to the occurrence in the flasks of agglomeration of the powder or its lack of consistent wettability, leading to lower values of Ni(aq). However, within each flask, the variability of the replicate analyses, expressed as a percentage of the standard deviation divided by the average value of Ni(aq), was less than 3%. The low standard deviation for each separate flask provides
confidence in the results of the ICP-MS method of analysis.
Among the five screening tests at pH 8, the average value of Ni(aq) was about 7 mg/L, with a standard deviation that amounted to 21% of the average, which is close to the anticipated among-flask variability of 20%. Within each test, the standard deviation was about 2% or less of the average value of Ni(aq). In tests 1, 2 and 3, the average values of Ni(aq) approach the calculated concentration of 6.9 mg/L. However, in tests 3 and 5, the average values of Ni(aq) are greater than the calculated concentration.
In transformation screening tests using the Draft OECD T/D Protocol for measuring the rate and extent of the transformation of metals and sparingly soluble inorganic compounds to bioavailable species, nickel carbonate hydroxide powder releases averages of about 7 ± 1.5 and 35 ± 11 mg/L of Ni(aq) at pH 8 and 6 in the aqueous media OECD 203 and dilute 10:1 OECD 203,
respectively. Given the amount of nickel released in the screening test, no further T/D P testing was conducted.
Applicant's summary and conclusion
- Executive summary:
We have applied the 24-hour screening test for metal compounds of the Draft OECD
Transformation/Dissolution (T/D) Protocol to nickel carbonate hydroxide powder. The T/D Protocol is
intended to measure the rate and extent of the transformation of metals and sparingly soluble inorganic
metal compounds to the bioavailable form. The transformation data, when compared to existing
ecotoxicity data, can be used in the hazard classification of the substance under consideration.
The screening tests at pH 6 show that, after 24 hours of agitation in dilute 10:1 OECD 203
medium, the nickel carbonate hydroxide powder releases total dissolved nickel concentrations in the range
of about 22 and 46 mg/L. At pH 8, the concentrations of total dissolved nickel ranged between 5.5 and
9.3 mg/L in the regular OECD 203 medium. Given the relatively high levels of dissolved nickel obtained in
the screening test, the seven-day and 28-day transformation tests provided for in the Draft T/D Protocol
were not conducted.
The specific surface area of the nickel carbonate hydroxide powder as measured by a nitrogen
adsorption-desorption technique was 199 m2/g. Thus the relatively high measured specific surface area of
the nickel carbonate hydroxide powder may be a factor in its reactivity in the aqueous media.
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