Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-419-9 | CAS number: 106-65-0
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Justification for classification or non-classification
Additional information
In accordance with REACH Regulation 1907/2006, Annex X, Column 2, a carcinogenicity test may be required if the substance has a widespread dispersive use with frequent long-term human exposure and is classified as mutagenic or there is evidence from repeated dose studies that pre-neoplastic lesions may be induced.
Waiving of the data requirement is justified as the substance is used in closed systems, it is not classified as mutagenic and repeated dose studies have shown no evidence of the induction of pre-neoplastic lesions alhough hyperplasia of the olfactory epithelium was seen as an irritant response
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
