Tris(2-ethylhexyl) phosphate

Long-term toxicity to fish

Administrative data

Endpoint:

fish early-life stage toxicity

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING
According to REACH Annex IX, 9.1 (aquatic toxicity), long-term testing shall be proposed if the chemical safety assessment indicates the need to investigate further the effects on aquatic organisms. The studies available indicate that in acute aquatic toxicity tests at 3 trophic levels there are no effects up to the limit of water solubility. Furthermore, in the two available long-term toxicity studies on Daphnia magna and algae, no adverse effects were identified at levels orders of magnitude higher than the limit of solubility, thus no environmental hazard was identified. Considering these results, testing on higher organisms, i.e. vertabrates, is scientifically unjustified (Annex VIII, 9.1.3) as substantial evidance suggests no adverse effect will occur during long term testing at the limit of solubility or at environmentally relevant exposure levels. This is further supported by a 14 d prolonged toxicity test conducted at 40 mg/L - this limit concentration determined when a dispersant was used, which showed no mortality or adverse effects.

Materials and methods

Test material

Test material information

Constituent 1

Reference substance name:

Tris(2-ethylhexyl) phosphate

EC Number:

201-116-6

EC Name:

Tris(2-ethylhexyl) phosphate

Cas Number:

78-42-2

Molecular formula:

C24H51O4P

IUPAC Name:

tris(2-ethylhexyl) phosphate