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EC number: 201-162-7
CAS number: 78-96-6
No data available
No studies on terrestrial organisms are
available for 1-aminopropan-2-ol (CAS 78-96-6).
In Annex X Section 9.4 of Regulation (EC) No
1907/2006, it is laid down that tests on terrestrial organisms shall be
proposed by the registrant if the chemical safety assessment indicates
the need to investigate further the effects on terrestrial organisms.
According to Annex IX and X, the choice of the appropriate tests depends
on the outcome of the chemical safety assessment. According to Annex I
of this regulation, the chemical safety assessment triggers further
action when the substance or the preparation meets the criteria for
classification as dangerous according to Directive 67/548/EEC or
Directive 1999/45/EC or CLP-Regulation (EC) No 1272/2008 or is assessed
to be a PBT or vPvB.
The hazard assessment of the substance
reveals neither a need to classify the substance as dangerous to the
environment, nor is it a PBT or vPvB substance, nor are there any
further indications that the substance may be hazardous to the
environment. In addition, indirect exposure to the soil compartment is
unlikely since the substance is readily biodegradable according to OECD
criteria. For substances being considered as „readily biodegradable“, it
can be assumed that they will be biologically degraded within the
STP-process. As the log Koc and log Kow of the substance are below 3, a
low adsorption potential is indicated (see IUCLID Ch. 5.4.1). Hence, an
adsorption to activated sludge is unlikely. Based on the low log Kow and
the low estimated BCF values, bioaccumulation in aquatic organisms is
not to be expected (see IUCLID Ch. 5.3.1).
In Annex XI Section 3, it is laid down that
testing in accordance with sections 8.6 and 8.7 of Annex VIII and in
accordance with Annex IX and Annex X may be omitted, based on the
exposure scenario(s) developed in the Chemical Safety Report
(“Substance-Tailored Exposure-Driven Testing”). In accordance with Annex
XI Section 3, it can be demonstrated in the risk assessment that the
manufacture and the use of the substance do not pose an unacceptable
risk for all environmental compartments as the risk characterization
ratios (RCRs) of the chemical safety assessment are below 1 for all
compartments (see Chemical Safety Report Ch. 9,10).
Consequently, no tests on soil organisms are
performed. The equilibrium partitioning method has been used for
assessing the hazard to soil organisms in accordance with Annex IX,
Section 9.4, Column 2 of Regulation (EC) No 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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