Registration Dossier
Registration Dossier
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EC number: 200-316-0 | CAS number: 57-14-7
Carcinogenicity
Administrative data
Description of key information
The substance is present in the following carcinogen lists:
- European harmonized classification: Carc. 1B; H350 (CLP)
- NIOSH: http://www.cdc.gov/niosh/topics/cancer/npotocca.html#d
- IARC: Group 2B: "Possibly carcinogenic to humans"
- NTP's 11th Report on Carcinogens: Part B: "Reasonably Anticipated to be a Human Carcinogen"
Carcinogenic Potency Database, for the substance, enables to identify the target organs below, all by oral administration.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Organ:
- kidney
- liver
- lungs
- vascular system
Justification for classification or non-classification
The substance is subject of a harmonized classification as a carcinogen: Carc. 1B; H350 (CLP).
Additional information
The substance is a carcinogen in animals and a suspected carcinogen in humans. Further data can be found in IARC monograph and are not required at this tonnage level.
Carcinogenicity: via oral route (target organ): cardiovascular / hematological: other; digestive: cecum; digestive: liver; respiratory: lung; urogenital: kidneys
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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