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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study follows current guideline. GLP not noted in report. Purity of test material not provided.
Qualifier:
according to
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
GLP compliance:
not specified
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
CYANOX® 1790 Antioxidant
IUPAC nomenclature - Tris(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl) isocyanurate
Synonym - [tris(4-t-butyl-3-hydroxy-2,6-dimethyl-benzyl)-s-triazine-2,4,6-(1H,3H,5H) trione]
Lot WP1031901
Appearance - White powder, odorless
CAS No. 40601-76-1
Molecular Formula - C42H57N3O6
Molecular Weight - 699.92 g/mole
Purity > 99%
Mass median aerodynamic diameter:
82 µm
Percentile:
D50
Mean:
86 µm
St. dev.:
1
Percentile:
D10
Mean:
25 µm
St. dev.:
2
Percentile:
D90
Mean:
143 µm
St. dev.:
4
No.:
#1
Size:
< 25 µm
Distribution:
> 8.1 - < 9 %
No.:
#2
Size:
< 50 µm
Distribution:
> 21.1 - < 22.9 %
No.:
#3
Size:
< 100 µm
Distribution:
> 66.2 - < 66.6 %
No.:
#4
Size:
< 150 µm
Distribution:
> 90.9 - < 92.9 %

The mean particle size is 86 microns as per Horiba light scattering analysis. Optical microscopy image correlates to the Horiba data. A representative image is provided below followed by the volume distribution plots.

 

Particle Size Summary of Test Substance

Run No.

% < Xmm

(mm)

X = 25

X = 50

X = 100

X = 150

Mean

Median

10thpercentile

90thpercentile

1

8.1

21.1

66.6

92.9

86

83

29

140

2

9.0

22.9

66.2

90.9

87

82

27

147

 

 

 

Conclusions:
The mean particle size is 86 µm with 10% of the particles < 25 µm and 90% of the particles > 143 µm.

Description of key information

The mean particle size of the test substance was determined to be 86 µm using a Horiba LA920 light scattering particle size analyzer and confirmed by optical microscopy.

Additional information

The mean particle size of the test substance is 86 µm with 10% of the particles < 25 µm and 90% of the particles > 143 µm.