Registration Dossier
Registration Dossier
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EC number: 219-470-5 | CAS number: 2440-22-4
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 964
- Report date:
- 1964
Materials and methods
- Type of study / information:
- Phototoxicity
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Each agent was applied to the backs of ten (10) men under occlusion for twenty-four (24) hours. A control site was treated with petrolatum. Then, one minimal erythema dose was given to the treated and control sites using the erythema producing radiation produced by the Westinghouse FS-20 lamp. Photo-toxicity is indicated by a marked flare at the sites treated by the test agents.
- GLP compliance:
- no
- Remarks:
- Study pre-dates GLP
Test material
- Reference substance name:
- 2-(2H-benzotriazol-2-yl)-p-cresol
- EC Number:
- 219-470-5
- EC Name:
- 2-(2H-benzotriazol-2-yl)-p-cresol
- Cas Number:
- 2440-22-4
- Molecular formula:
- C13H11N3O
- IUPAC Name:
- 2-(2H-1,2,3-benzotriazol-2-yl)-4-methylphenol
- Test material form:
- solid
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Tinuvin P
Results and discussion
Any other information on results incl. tables
A table of results is provided in the study report; however, the results were not fully described. It was concluded in the study report that CAS 2440 -22 -4 was not phototoxic.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
