Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 603-923-2 | CAS number: 135590-91-9
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Remarks:
- limited documentation.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
- Study type:
- health record from industry
- Endpoint addressed:
- not applicable
- Principles of method if other than guideline:
- Occupational medical surveillance of workers exposed to Mefenpyr-diethyl, performed every 3 years on a routine basis.
- GLP compliance:
- no
- Remarks:
- not applicable
Test material
- Reference substance name:
- diethyl 1-(2,4-dichlorophenyl)-5-methyl-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate
- EC Number:
- 603-923-2
- Cas Number:
- 135590-91-9
- Molecular formula:
- C16H18Cl2N2O4
- IUPAC Name:
- diethyl 1-(2,4-dichlorophenyl)-5-methyl-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate
Constituent 1
Method
- Type of population:
- occupational
- Ethical approval:
- not applicable
- Details on study design:
- Occupational medical surveillance of workers exposed to Mefenpyr-diethyl, performed every 3 years on a routine basis, not directly related to exposures. The examinations included physical, orientating neurological examinations (reflexes, sensibility, coordination), laboratory examinations (blood count, AST, ALT, y-GT, creatinin, urine) and technical examinations (audiometrie, sonography, spirometry, ECG) of 38 workers.
Results and discussion
- Results:
- Occupational medical surveillance of workers exposed to Mefenpyr-diethyl, performed every 3 years on a routine basis, not directly related to exposures, did not reveal any unwanted effects in the workers. During the production period(s) from 2000 to 2004 no accidents with Mefenpyr-diethyl occurred in the workers, and no consultations of the Medical Department due to work or contact with Mefenpyr-diethyl were required.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
