Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
secondary source
Title:
No information
Year:
1983
Bibliographic source:
Medicamentos de Actualidad. Vol. 19, Pg. 649, 1983

Materials and methods

Principles of method if other than guideline:
Method not published
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
L-Lysine, 2-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]acetate (1:1)
EC Number:
617-268-5
Cas Number:
81919-14-4
Molecular formula:
C22H28N4O5
IUPAC Name:
L-Lysine, 2-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]acetate (1:1)

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
3 100 mg/kg bw
Clinical signs:
other: Lungs, thorax or respiration: dyspnea Behavioral: ataxia

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU