Registration Dossier
Registration Dossier
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EC number: 211-077-7 | CAS number: 629-15-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 h): 38 mg/L for Pseudokirchneriella subcapitata based on growth rate (nominal; OECD 201)
NOEC (72 h): 10 mg/L for Pseudokirchneriella subcapitata based on growth rate (nominal; OECD 201)
Key value for chemical safety assessment
Additional information
One experimental study investigating the effects of ethylene diformate (CAS 629-15-2) to freshwater algae is available (Vryenhoef, 2013). The study was performed according to OECD 201 under GLP conditions using the freshwater algae Pseudokirchneriella subcapitata. Nominal test substance concentrations up to 100 mg/L were applied. The substance was found to hydrolyse in test medium with an approximate half-life of 4 h. The analytical measurement with gas chromatography (GC) revealed a decline in test concentrations. Therefore, the possible effects of the parent substance and the hydrolysis products were assessed in this study. After an exposure of 72 h an EC50 (72 h) of 38 mg/L and a NOEC (72 h) of 10 mg/L were calculated based on growth rate. Complete hydrolysis of the parent test item did not occur and toxicity cannot be attributed to the parent test item, the hydrolysis product or a mixture of the two, therefore, it was considered appropriate to calculate the results based on nominal parent test item concentrations only.
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