Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The LC50 of a formulated product containing the registered substance was found to be 646 mg/l. The formulated product contains 44.7% of the registered substance. Assuming a linear dose-response relationship, 44.7% of 646 mg/l = 288.76 mg/l. Therefore the LC50 for the registered substance is proposed to be 288.76 mg/l. The registered substance is not considered to be toxic to aquatic invertebrates based on the findings of this study.

Key value for chemical safety assessment

Marine water invertebrates

Marine water invertebrates
Dose descriptor:
LC50
Effect concentration:
288.76 mg/L

Additional information

The acute toxicity of the a formulated product containing the registered substance to aquatic invertebrates was determined in accordance with the draft ISO Testing Method 14669:1999 (E). Nominal test concentrations of the test material were prepared over the range 200 mg/l to 2000 mg/l. The marine invertebrate Acartia tonsa was exposed to the test concentrations in order to determine the concentration which killed 50% of the copepods over 48 hours (LC50). The lowest concentration of test material producing 100% mortality could not be determined from this study. All concentrations of test material produced some mortality in this study. There was some evidence of a dose response in this study. All parameters measured in this study lay within the acceptable tolerance limits. The test material is not considered toxic to Acartia tonsa within the conditions of this study. The LC50 of the formulated product was found to be 646 mg/l/ The formulated product contains 44.7% of the registered substance. Assuming a linear dose-response relationship, 44.7% of 646 mg/l = 288.76 mg/l. Therefore the LC50 for the registered substance is proposed to be 288.76 mg/l. The registered substance is not considered to be toxic to aquatic invertebrates based on the findings of this study. In addition, an equivalent study was conducted on a formulated product containg a structurally similar substance to the registered substance (a formulated product containing tosyl salt). The 48 hour LC50 of the read-across material was found to be 1626.1 mg/l. The formulated product contains 44.7% of the registered substance. Assuming a linear dose-response relationship, 44.7% of 1626.1 mg/l = 726.87 mg/l. Therefore the LC50 for the registered substance is proposed to be 726.87 mg/l. The N-methyl salt is not considered to be toxic to aquatic invertebrates. The 48 hour LC50 of triethanolamine was found to be 1951.4 mg/l. Triethanolamine is not considered to be toxic to aquatic invertebrates.