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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
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- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Determination of the Abiotic Degradation of FAT 40858/A TE (Hydrolysis as a Function of pH)
Key value for chemical safety assessment
Additional information
In a preliminary test the test item was dissolved in aqueous solutions buffered at pH 4, 7 and 9 and incubated at 50 ± 0.5 °C for maximum of 5 days.
No significant reduction of the test item concentration was observed in the samples incubated at pH 4.
In the incubated samples at pH 7 a significant reduction of the test item concentration was observed.
In the incubated samples at pH 9 the test item degraded rapidly. No test item related signal could be found in the freshly prepared samples.
A main test was performed to determine the half-life time of FAT 40858/A TE at pH 7. No main test was performed at pH 4 and pH 9.
Amain test was performed in buffered solutions at pH 7. The test item was dissolved and incubated at 23°C, 40 °C and 50 °C.The concentration of the test item was determined as a function of time. The logarithms of the concentration relation (co/ct) were plotted against the time. A pseudo first order reaction was assumed. The correlation coefficients were calculated and the reaction constants and half lifes were calculated from regression data at each temperature.
For reaction at pH 7 the Arrhenius relationship was
calculated based on data generated at 23, 40 and 50 °C. Logarithm of the
rate constants were plotted against the reciprocal of the absolute
temperature.
Following relation was found:
pH 7: ln k = - 11866 * 1/T + 36
Degradation Products: The UV-chromatograms showed several degradation products as signal eluting prior to the test item signal. In agreement with the sponsor, no identification of the metabolites was performed.
Conclusion:
The test item is stable at pH 4.
At pH 7, the test item is degraded by hydrolysis. The half life of reaction at 23 °C was determined to be 23 h at pH 7.
At pH 9 the test item is supposed to degrade immediately.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.