Registration Dossier
Registration Dossier
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EC number: 264-431-8 | CAS number: 63721-05-1
Endpoint summary
Administrative data
Description of key information
Oral: LD50 > 5000 mg/kg bw, male/female, rat, OECD401, Gardner 1988
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 5 000 mg/kg bw
Additional information
Oral:
A single oral toxicity study conducted under GLP according to guideline OECD 401 is available (Gardner 1988). The study is considered to be relevant, reliable (Klimisch 1) and adequate for the purposes of risk assessment, classification and labeling.
Since none of the three doses elicited mortalities above 40% in either sex, the LD50 of the test material in rats was estimated to be >5000 mg/kg bw.
Justification for classification or non-classification
The available value for the acute oral toxicity (rat), LD50>5000 mg/kg bw does not lead to a corresponding classification of the substance, according to the criteria given in Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC, Annex VI, 3.2.1-3.2.3.
The available value for the acute oral toxicity (rat), LD50>5000 mg/kg bw does not lead to a corresponding classification of the substance, according to the criteria in Regulation (EC) No. 1272/2008, Annex I, Part 3, 3.1.2.
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