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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Administrative data

Description of key information

In the case report the patch test was positive to 1%, 0.1% and 0.01% quinine dihydrochloride. Thus, quinine dihydrochloride can be considered a contact sensitizer.

Additional information

In this case report 15 of 23 workers suggested that the skin eruption had been work-related. In a patch-test 12 of these 15 patients suspected to be sensitized to quinine or quinidine only one positive patch test were obtained for quinine dihydrochloride. In the case the patch test was strongly positive for 1%, 0.1% and 0.01% quinine dihydrochloride. Photo patch test were positive at 1% and 0.1 % quinine dihydrochloride. Thus, quinine dihydrochloride can be considered a contact sensitizer.