4-nitroaniline

Endpoint summary

Additional information

Stability:

Phototransformation in air:-

The atmospheric oxidation half-life of4-nitroaniline was estimated using the level III multimedia model. It was estimated that the substance is not persistent in air medium as the half life period of4-nitroaniline in air is only 1.2 days. This indicates that4-nitroanilineis rapidly phototransformed in air.

Hydrolysis:-

The Hydrolysis rate constant of4-nitroanilineis estimated to be 0.0000000000134536 cm3/molecule-sec. at half life of the 9.54 Hrs.The estimated half life of the substance indicates that the substance is moderately hydrolysable.

Biodegradation:-

Biodegradation in water:-

4-nitroanilineis 50% biodegradable in water in 38 days (half-life) indicating4-nitroanilineis readily biodegradable in water.

Biodegradation in water and sediment:

Based on the Level III Fugacity Model, the half life period of the4-nitroanilinewas estimated. The half period of4-nitroanilinein water is 912 hrs (38 days) therfore it is considered that the substance will qualify as not persistent as the half life does not exceed the EPA criteria of 60 days. So, it can be confirmed that the substance is readily biodegradable in water medium where as in sediment the half life is 8160 hrs (340 days). Based on this value, it can be inferred that the substance is persistent in sediment medium and is not readily biodegradable probably due to the anaerobic conditions existing in most sediments. However, it can be observed that4-nitroanilinedoes not diffuse in the sediment medium since it's percentage in the sediment medium is reported to be 0%.

Biodegradation in soil:

Based on the Level III Fugacity Model the half life period of the4-nitroanilinewas estimated. As per the values it was observed that in general4-nitroanilinepersistence time is 1680 hr. The half life period of4-nitroanilinein soil is 1800 hrs and based on this value it is indicated that the chemical is persistent in soil medium.

Bioaccumulation:-

Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure. The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration factor (BCF).

 

The estimated BCF of the key study was obtained to be 3.8.Supporting studies indicate the BCF to be between 3.5 to 3.8. This low value of BCF of4-nitroanilineindicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 1000.

Adsorption/Desorption

Soil Adsorption Coefficient i.e Koc value of 4-nitroaniline was estimated as 109.1 L/kg by means of MCI method. This indicates that 4-nitroaniline will moderately adsorb to the organic carbon fraction of the soil and will have a tendency to move with the water content in the soil. This value of 109.1 when converted at 20°C works out to be 87.28

Henry's Law constant

Henry's Law states that at a constant temperature, the amount of a given gas that dissolves in a given type and volume of liquid is directly proportional to the partial pressure of that gas in equilibrium with that liquid. Henrys Law Constant of4-nitroanilinewhich is a solid at 25 deg C is 0.000761 Pa m³/mol