Registration Dossier
Registration Dossier
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EC number: 200-872-4 | CAS number: 75-46-7
Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water and sediment: simulation testing, other
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- No information
- Author:
- Syracuse Research Corporation
- Year:
- 2 006
- Bibliographic source:
- cited in National Library of Medicine. Hazardous Substances Data Bank, HSDB/5207, accessed January 18, 2006.
- Reference Type:
- publication
- Title:
- Environmental Fate and Exposure Studies Development of a PC-SAR for Hydrolysis: Esters, Alkyl Halides and Epoxides.
- Author:
- Mill T, Haag W, Penwall P, Pettit T, and Johnson H
- Year:
- 1 987
- Bibliographic source:
- EPA Contract No. 68-02-4254. Menlo Park, CA: SRI International (cited in National Library of Medicine. Hazardous Substances Data Bank, HSDB/5207, accessed January 18, 2006).
Materials and methods
- Principles of method if other than guideline:
- Accepted calculation method
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Trifluoromethane
- EC Number:
- 200-872-4
- EC Name:
- Trifluoromethane
- Cas Number:
- 75-46-7
- Molecular formula:
- CHF3
- IUPAC Name:
- trifluoromethane
- Details on test material:
- - Purity: not reported
Constituent 1
Results and discussion
% Degradation
- Remarks on result:
- other: not biodegradable
Any other information on results incl. tables
A base-catalyzed second-order hydrolysis rate constant of 4.3X10E-2 L/mol-sec (SRC, n.d.) was estimated using a structure estimation method (Mill et al., 1987); this corresponds to half-lives of 5.1 years and 190 days at pH values of 7 and 8, respectively (Mill et al., 1987; SRC, n.d.) suggesting that hydrolysis is not expected to be an important process (SRC, n.d.).
Applicant's summary and conclusion
- Conclusions:
- A base-catalyzed second-order hydrolysis rate constant of 4.3X10E-2 L/mol-sec was estimated using a structure estimation method; this corresponds to half-lives of 5.1 years and 190 daysat pH values of 7 and 8, respectively suggesting that hydrolysis is not expected to be an important process.
- Executive summary:
A base-catalyzed second-order hydrolysis rate constant of 4.3X10E-2 L/mol-sec was estimated using a structure estimation method; this corresponds to half-lives of 5.1 years and 190 daysat pH values of 7 and 8, respectively suggesting that hydrolysis is not expected to be an important process.
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