Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 206-056-4 | CAS number: 298-07-7
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: secondary source (insufficient documented)
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Summary tables of biological tests
- Author:
- Anonymous
- Year:
- 1 957
- Bibliographic source:
- National Research Council Chemical-Biological Coordination Center, 9, 132, 1957, cited in NIOSH/RTECS
Materials and methods
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
Test material
- Reference substance name:
- Bis(2-ethylhexyl) hydrogen phosphate
- EC Number:
- 206-056-4
- EC Name:
- Bis(2-ethylhexyl) hydrogen phosphate
- Cas Number:
- 298-07-7
- Molecular formula:
- C16H35O4P
- IUPAC Name:
- bis(2-ethylhexyl) hydrogen phosphate
- Details on test material:
- Phosphoric acid, bis(2-ethylhexyl)ester
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- propylene glycol
- Doses:
- 31.3, 62.5, 125, 250, 500 mg/kg bw
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 62.5 mg/kg bw
- Based on:
- not specified
Any other information on results incl. tables
dose mg/kg mortality
31.3 0 %
62.5 50%
125 100%
250 100%
500 100%
Applicant's summary and conclusion
- Executive summary:
LD50 of bis(2-ethylhexyl) hydrogen phosphate is 62.5 mg/kg (no further data)
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