Registration Dossier
Registration Dossier
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EC number: 464-320-6 | CAS number: 423772-95-6
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- 1. Test temperature was taken as a one spot point during the experience. For this reason. 22°C ± 2°C is indicative. 2.As one of the 48 hours assays shows an unreliable result, only five results are taken to define the solubility of the test item in water
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- 1.Test temperature was taken as a one spot point during the experience .For this reason ,22°C ± 2°C is indicative. 2.As one of the 48 hours assay shows an unreliable result, only five results are taken to define the solubility of the test item in water
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- 2003-03-27
- Type of method:
- flask method
- Water solubility:
- ca. 2.3 mg/L
- Temp.:
- 22 °C
- pH:
- 5
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The solubility in water of the test item is found to be 2.3 mg/L - Executive summary:
The objective of this study is to determine the water solubility of the test item at a given temperature after a hydrosolubility test (CEE A6).
The solubility in water of the test item was specified by the saturation mass concentration of the test item in water at a given temperature using the flask method.
The quantification of the test item was determined, after derivatization, by gas-liquid chromatography (CPG) using a flame ionisation detector (FID).
The solubility in water of the test item was found to be 2.3 mg/L
Reference
Description of key information
The objective of the study was to determine the water solubility of the test item at a given temperature after a hydrosolubility test (CEE A6).
The solubility in water of the test item was specified by the saturation mass concentration of the test item in water at a given temperature using the flask method.
The quantification of the test item was determined, after derivatization, by gas-liquid chromatography (CPG) using a flame ionisation detector (FID).
The solubility in water of the test item was found to be 2.3 mg/L
Key value for chemical safety assessment
- Water solubility:
- 2.3 mg/L
- at the temperature of:
- 22 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
