Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 456-080-6 | CAS number: -
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG, B.2; OECD 403
- GLP compliance:
- yes
- Limit test:
- no
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- Physical form of substance: S
Mass median aerodynamic diameter (for liq.+solid aerosol):
MMAD: 6,51 µm
Test animals
- Species:
- other: rat, Wistar Hsd Cpb:WU (SPF)
Administration / exposure
- Vehicle:
- other: Luft "ENGLISH" Air
- Details on inhalation exposure:
- nose-only
- Duration of exposure:
- 4 h
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 4.575 mg/L air
- Exp. duration:
- 4 h
- Mortality:
- Male: 0 mg/L; Number of animals: 5; Number of deaths: 0
Male: 5 mg/L; Number of animals: 5; Number of deaths: 0
Female: 0 mg/L; Number of animals: 5; Number of deaths: 0
Female: 5 mg/L; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: Mortality did not occur in any group. All rats tolerated the exposure without specific signs. Body weight development between the control and the exposure groups is not significantly influended by the test
- Gross pathology:
- Effects on organs:
Necropsy findings were not observable.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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