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EC number: 617-298-9 | CAS number: 82097-50-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
Six simulation tests on the biodegradation in water and sediment are available and included as supporting information. More details are provided in the additional information.
Key value for chemical safety assessment
Additional information
Studies required in Annex VII and some other studies required for higher tonnage are available. All the studies available have been included in the dossier and some of them are considered in the PBT assessment. Therefore, all studies are summarized below. Six GLP studies performed to standard guidelines are available for this endpoint. Three of these studies were performed in the freshwater-sediment system under aerobic conditions according to OECD TG 308 and/or EPA 162-4. The test conditions and results of these aerobic studies were summarized in the table below.
Table. DT50 values for the substance in freshwater-sediment system under aerobic standard test conditions
Test system | Test conditions | Mineralisation / Non- extractable residues / Major metabolites (%) |
Compartment | DT50 [d] – Kinetic model | Author / Year |
Calwich, Derbyshire, UK | 14C-triazine- labelled test substance, Aerobic, 20°C, darkness, 100 days, pH water 8.0 | CO2: 1.9% after 100d Non-extr.: max.9.5% after 59d declining to 6.7% after 100d Maj. Met.:M1 – max. 28.6% after 100d, M2 – max. 8.4% after 100d |
Water |
70.1- (SFO) | Dixon & Gilbert, 2010 |
Calwich, Derbyshire, UK | 14C-triazine- labelled test substance, Aerobic, 20°C, darkness, 100 days, pH water 8.0 | CO2: 1.9% after 100d Non-extr.: max.9.5% after 59d declining to 6.7% after 100d Maj. Met.:M1 – max. 28.6% after 100d, M2 – max. 8.4% after 100d |
Total system |
95.9 (SFO) | Dixon & Gilbert, 2010 |
Calwich, Derbyshire, UK | 14C-phenyl-labelled test substance, Aerobic, 20°C, darkness, 100 days, pH water 8.0 | CO2: 2.0% after 100d Non-extr.: max 10.9% after 59d declining 9.5% after 100d Main Met.:M1 – max. 27.3% after 100d, M3 – max. 6.1% after 100d |
Water |
65.8 (SFO) | Dixon & Gilbert, 2010 |
Calwich, Derbyshire, UK | 14C-phenyl-labelled test substance, Aerobic, 20°C, darkness, 100 days, pH water 8.0 | CO2: 2.0% after 100d Non-extr.: max 10.9% after 59d declining 9.5% after 100d Main Met.:M1 – max. 27.3% after 100d, M3 – max. 6.1% after 100d |
Total system |
87.7 (SFO) | Dixon & Gilbert, 2010 |
Swiss Lake, Chatsworth, Derbyshire, UK | 14C-triazine- labelled test substance, Aerobic, 20°C, darkness, 100 days, pH water 6.6 | CO2: 1.8% after 100d Non-extr.: max 4.9% after 100d Maj. Met.: M1 – max. 10.4% after 100d, M2 – max. 10.7% after 100d |
Water |
139.1- (SFO) | Dixon & Gilbert, 2010 |
Swiss Lake, Chatsworth, Derbyshire, UK | 14C-triazine- labelled test substance, Aerobic, 20°C, darkness, 100 days, pH water 6.6 | CO2: 1.8% after 100d Non-extr.: max 4.9% after 100d Maj. Met.: M1 – max. 10.4% after 100d, M2 – max. 10.7% after 100d |
Total system |
195.4 (SFO) | Dixon & Gilbert, 2010 |
Swiss Lake, Chatsworth, Derbyshire, UK | 14C-phenyl-labelled test substance, 20°C, darkness, 100 days, pH water 6.6 | CO2: 2.2% after 100d Non-extr.: max 6.8% after 100d Main Met.: M1– max. 8.1% after 100d, M3 – max. 4.0% after 100d |
Water |
131.5 (SFO) | Dixon & Gilbert, 2010 |
Swiss Lake, Chatsworth, Derbyshire, UK | 14C-phenyl-labelled test substance, 20°C, darkness, 100 days, pH water 6.6 | CO2: 2.2% after 100d Non-extr.: max 6.8% after 100d Main Met.: M1– max. 8.1% after 100d, M3 – max. 4.0% after 100d |
Total system |
214.5 (SFO) | Dixon & Gilbert, 2010 |
Pond system, Illinois, USA | 14C-triazine- labelled test substance, Aerobic, 25°C, darkness, 30 days, pH water 8.1 | CO2: <0.1 after 30d Non-extr.: 0.0 during study Maj. Met.:M2 – max. 11.7% after 30d |
Water |
39- (linear SFO) | Spare, 1993a |
Pond system, Illinois, USA | 14C-triazine- labelled test substance, Aerobic, 25°C, darkness, 30 days, pH water 8.1 | CO2: < 0.1 after 30d Non-extr.: 0.0 during study Maj. Met.:M2 – max. 11.7% after 30d |
Total system | 44 (linear- SFO) | Spare, 1993a |
Pond system, Illinois, USA | 14C-phenyl-labelled test substance, Aerobic, 25°C, darkness, 30 days, pH water 8.1 | CO2: 6.2 after 30d Non-extr.: 0.0 during study Maj. Met.:none |
Water |
30 (SFO) | Spare, 1993b |
Pond system, Illinois, USA | 14C-phenyl-labelled test substance, Aerobic, 25°C, darkness, 30 days, pH water 8.1 | CO2: 6.2 after 30d Non-extr.: 0.0 during study Maj. Met.:none |
Total system |
38 (SFO) | Spare, 1993b |
|
| Geomean |
Water | 68.0 |
|
|
| Geomean |
Total system | 91.6 |
|
The other three studies were performed in the freshwater-sediment system under anaerobic conditions according to OECD TG 308 and/or EPA 162-3 (Dixon & & Gilbert 2012, Spare 1993c and Spare 1993d). In the study performed by Dixon & Gilbert (2012), two water/sediment systems (Calwich Abbey and Swiss Lake) were used. The 14C-triazine labelled test substance and 14C-phenyl labelled test substance were applied separately to two separate systems at a nominal rate of 0.44 μg/mL. The water-sediment samples were incubated under anaerobic conditions in the laboratory and maintained in the dark at 20 ± 1°C for 367 days. The amount of produced CO2, radioactivity and degraded metabolites were analysed using LSC, HPLC and TLC. The DT50 values for the total system were determined to be79.3 and 245.7 days for the [Phenyl-14C]-labelled test substance in the Calwich Abbey and Swiss lake systems, respectively. The DT50 values for the total system were determined to be 89.4 and 280.6 days for the [Triazinyl-14C]- labelled test substance in the Calwich Abbey and Swiss lake systems, respectively.
In the studies performed by Spare (1993 c and 1993d), one water/sediment system (Illinois pond water) was used. Both studies were maintained in the dark at 25 ± 1°C for 366 days. The dose rate of the 14C-phenyl labelled test substance to the water was 9.83 ppm for anaerobic non-sterile and 9.16 ppm for the anaerobic sterile incubations (Spare 1993c). The half-life of the test substance was determined to be 44 days with a rate constant of 1.6E-02 days-1. The dose rate of the 14C- triazine labelled test substance to the water was 9.63 ppm for anaerobic non-sterile and 9.68 ppm for the anaerobic sterile incubations (Spare 1993d). The half-life of the test substance was determined to be 47 days with a rate constant of 1.5E-02 days-1.
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