Registration Dossier
Registration Dossier
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EC number: 208-436-5 | CAS number: 528-50-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May 24, 2022 - ongoing
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- July 27, 1995
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- column elution method
- Specific details on test material used for the study:
- LOT No.: L1021174
Appearance: white, dry powder
Expiry date: 28 October 2023
Storage condition: at room temperature, protected from light
Safety precautions: according to MSDS
Purity: 99.54 % - Key result
- Water solubility:
- ca. 117 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- >= 6.69 - <= 7.13
- Conclusions:
- In a GLP-compliant study according OECD TG 105, the water solubility of cellobiose was determined as 117 g/L.
- Executive summary:
In this study the water solubility of Cellobiose was determined at 20 ± 1 °C using the flask method.
The analytical method used for the quantification of test item concentration in water solubility samples was based on HPLC with MS/MS detection .
Specificity of the method was acceptable, no interfering peaks were observed at the retention time of the analyte and the internal standard.
Linearity was acceptable over the range of 10 – 1000 ng/mL. The accuracy values of the calibrators and quality control samples were acceptable.
Based on the measured concentrations, the solubility of Cellobiose in water is 117 mg/mL at 20 ± 1°C.
Reference
Description of key information
In a GLP-compliant study according OECD TG 105, the water solubility of cellobiose was determined as 117 g/L.
Key value for chemical safety assessment
- Water solubility:
- 117 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
