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EC number: 264-980-3 | CAS number: 64628-44-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in water
Administrative data
- Endpoint:
- phototransformation in water
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 23.08.1991 to 18.09.1991
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- This study was conducted to GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
- Study type:
- direct photolysis
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Phototransformation of Chemicals in Water, Part A: Direct Phototransformation, UBA,
- Version / remarks:
- 1990
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-chloro-N-[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]benzamide
- EC Number:
- 264-980-3
- EC Name:
- 2-chloro-N-[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]benzamide
- Cas Number:
- 64628-44-0
- Molecular formula:
- C15H10ClF3N2O3
- IUPAC Name:
- 3-(2-chlorobenzoyl)-1-[4-(trifluoromethoxy)phenyl]urea
1
Study design
- Radiolabelling:
- no
- Analytical method:
- high-performance liquid chromatography
- Light source:
- other: mercury immersion lamp - polychromatic light
- Light spectrum: wavelength in nm:
- 295 - <= 490
- Details on light source:
- The degradation experiment was conducted in a merrygo-round irradiation apparatus, fitted with a mercury immersion lamp. Higher-energy UV-rays below 295 nm were quantitatively absorbed by the incorporation of a filter tube.
- Details on test conditions:
- The quantum yield of the direct photodegradation of triflumuron in aqueous solution was determined in polychromatic light according to the ECETOC-method. The degradation experiment was conducted in a merrygo-round irradiation apparatus, fitted with a mercury immersion lamp. Higher-energy UV-rays below 295 nm were quantitatively absorbed by the incorporation of a filter tube. The quantum yield was calculated by means of the computer program QUANT. Besides the quantum yield, the absorption of the compound in the range of the tropospheric sunlight spectrum and the geographic, climatic, seasonal and matrix-specific marginal conditions are important factors influencing the degradation of the substance by direct photodegradation. The so-called environmental half-life for different marginal conditions can be assessed by means of arithmetic models (GC-Solar computer model by Zepp & Cline3 (1977) and the computer program according to Frank and Klöpffer4 (1985).
Preparation of solutions:
Experiments without using solvents are very problematic (adsorption effects) due to the extremely low water solubility of triflumuron. Usually the highly pure acetonitrile used remains neutral in photodegradation experiments.
Stock solution:
An amount of 21.0 mg test substance was dissolved in 100 ml acetonitrile. An aliquot of 2.5 mL of this stock solution was diluted with 47.5 ml acetonitrile and 50 mL water to a standard solution containing 5.25 mg active ingredient per liter water/acetonitrile 1:1 (v:v). The purity of the substance was checked by HPLC.
Solutions for the UV-absorption spectra:
Solutions in different solvents were used for recording UV-absorption spectra. The UV-absorption spectrum of a solution of 5.25 mg triflumuron/1 water/acetonitrile (1:1, v:v) was used for the calculation of the quantum yield.
Solutions for the photodegradation experiments:
The stock solution was diluted with water/acetonitrile (1:1;v:v). The evaluation of the HPLC analyses on the basis of external standard yielded 5.73 and 5.64 mg triflumuron per 1 water/acetonitrile (1:1; v:v), resp., as initial concentration for the two degradation experiments.
Performance of the photodegradation experiment:
The merry-go-round irradiation apparatus was started about 30 min. before beginning the exposure of the samples in order to guarantee a constant radiation of the light source as well as a constant sample temperature (room temperature) already at the beginning of the experiment. Subsequently only the merry-go-round but not the lamp or the cycle cooling was switched off for entering or removing of samples.
After the equilibration phase of the system, 2 measuring cuvettes with 3.0 mL (A) each were first entered and exposed for 10.0 min. After that the measuring cuvettes containing 3.0 mL test solution (5.1.3) each were swiftly placed onto the 10 positions of the merry-go-round. Scattered over a period of 7.5 hours, 1 sample each was removed and clearly marked (study-number, duration of exposure, test number).
Towards the end of the test period two actinometer samples were placed on positions of the merry-go-round meanwhile having become unoccupied and these were exposed for 10 min.
Results and discussion
- Quantum yield (for direct photolysis):
- 0.009
Dissipation half-life of parent compoundopen allclose all
- Key result
- DT50:
- 8.45 h
- Test condition:
- Experiment 1
- Key result
- DT50:
- 9.52 h
- Test condition:
- Experiment 2
- Transformation products:
- yes
- Remarks:
- 2-chlorobenzamide was formed during photochemical degradation.
- Details on results:
- The UV-absorption spectrum showed a main maximum at 200 nm. From the UV absorption data and the kinetic results of two photodegradation experiments in a merry-go-round irradiation apparatus the quantum yield was calculated to be 0.0095.
The resulting quantum yield and UV absorption data in aqueous solution were used to estimate the environmental half-life of triflumuron concerning direct photodegradation in water by two different simulation models The results of modelling indicate that direct photodegradation in aqueous solution contributes to the overall elimination of triflumuron in the environment to low extent only and that the environmental half-lives concerning direct photodegradation ranges from two months to more than one year, for the period of main use.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- The study is acceptable
- Conclusions:
- This study investigated the photodegradation of triflumuron in water. The quantum yield was calculated to be 0.0095. DT50 values of 8.45-9.52 hours were calculated.
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