Nickel Cobalt Manganese Hydroxide

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Automatic calculation with MeClas tool

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

other: software

Title:

Unnamed

Year:

2020

Materials and methods

Principles of method if other than guideline:

Aquatic toxicity of pNMC hydroxide was determined by classifying based on Mixture rules from EU CLP (Tier 2 = additivity of soluble components (T/Dp data) to derive Hazard class) and back calculation to the corresponding EC50.

Test material

Test material information

1

Reference substance name:

Nickel Cobalt Manganese Hydroxide

EC Number:

839-353-8

Cas Number:

189139-63-7

Molecular formula:

Molecular formula: Ni1-x-yMnxCoy(OH)2, Stoechiometry of (Me = Ni + Co + Mn) equals 1, ranges of the elements approx. as: Ni/Me = 0.25 – 0.95 Mn/Me = 0.02 – 0.40 Co/Me = 0.02 – 0.40 OH = 2.00

IUPAC Name:

Nickel Cobalt Manganese Hydroxide

Constituent 1

Reference substance name:

Manganese dihydroxide

Cas Number:

18933-05-6

Molecular formula:

Mn(OH)2

IUPAC Name:

Manganese dihydroxide

Constituent 2

Reference substance name:

Cobalt dihydroxide

EC Number:

244-166-4

EC Name:

Cobalt dihydroxide

Cas Number:

21041-93-0

Molecular formula:

CoH2O2

IUPAC Name:

cobalt(2+) dihydroxide

Constituent 3

Reference substance name:

Nickel dihydroxide

EC Number:

235-008-5

EC Name:

Nickel dihydroxide

Cas Number:

12054-48-7

Molecular formula:

H2NiO2

IUPAC Name:

nickel(2+) dihydroxide

Test material form:

solid: particulate/powder

Specific details on test material used for the study:

Generic composition, using the typical or maximum concentration for each elemental consituent.

Results and discussion

Effect concentrations

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

<= 1 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

other: most sensitive species

Any other information on results incl. tables

According to MeClas, the substance is classified as Aq.Acute Cat.1 to the environment.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

Good quality estimate of the L/EC50 of generic pNMC hydroxide.
The substance is classified as Aq.Acute Cat.1 to the environment resulting in a EC50 <= 1 mg/L.

Executive summary:

The study provided a conservative estimate of the effect concentration, derived on basis of the classification outcome (mixture toxicity rules) from a reasonable worst-case sample of the substanceusing dissolution data that were generated with a pNMC hydroxide-sample. 

Validity of the model used:

1. Defined endpoint: the endpoint is a REACH compliant defined endpoint

2. Unambiguous algorithm: EU CLP guidance based summation formula to determine classification, followed by back-calculation to related hazard criteria

3. Applicability domain: applicable to classify complex metal containing materials. 

4. Mechanistic interpretation - metal species: the tool translates the elemental composition into a mineralogical composition relevant for classification.